Evidence map›Paper›PMID 38667768›Full record

ArticleMarine drugs2024

Glucoregulatory Properties of a Protein Hydrolysate from Atlantic Salmon (

Christian Bjerknes, Sileshi Gizachew Wubshet, Sissel Beate Rønning, Nils Kristian Afseth, Crawford Currie, Bomi Framroze, Erland Hermansen

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christian BjerknesHofseth Biocare ASA, Keiser Wilhelms Gate 24, 6003 Ålesund, Norway.
Sileshi Gizachew WubshetNofima AS, Osloveien 1, 1433 Ås, Norway.
Sissel Beate RønningNofima AS, Osloveien 1, 1433 Ås, Norway.ORCID 0000-0002-2255-0172
Nils Kristian AfsethNofima AS, Osloveien 1, 1433 Ås, Norway.
Crawford CurrieHofseth Biocare ASA, Keiser Wilhelms Gate 24, 6003 Ålesund, Norway.ORCID 0000-0002-4441-5262
Bomi FramrozeHofseth Biocare ASA, Keiser Wilhelms Gate 24, 6003 Ålesund, Norway.ORCID 0000-0002-5251-8982
Erland HermansenHofseth Biocare ASA, Keiser Wilhelms Gate 24, 6003 Ålesund, Norway.
Nofima · NONorwegian University of Science and Technology · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic disorders are increasingly prevalent conditions that manifest pathophysiologically along a continuum. Among reported metabolic risk factors, elevated fasting serum glucose (FSG) levels have shown the most substantial increase in risk exposure. Ultimately leading to insulin resistance (IR), this condition is associated with notable deteriorations in the prognostic outlook for major diseases, including neurodegenerative diseases, cancer risk, and mortality related to cardiovascular disease. Tackling metabolic dysfunction, with a focus on prevention, is a critically important aspect for human health. In this study, an investigation into the potential antidiabetic properties of a salmon protein hydrolysate (SPH) was conducted, focusing on its potential dipeptidyl peptidase-IV (DPP-IV) inhibition and direct glucose uptake in vitro. Characterization of the SPH utilized a bioassay-guided fractionation approach to identify potent glucoregulatory peptide fractions. Low-molecular-weight (MW) fractions prepared by membrane filtration (MWCO = 3 kDa) showed significant DPP-IV inhibition (IC

Indexed as

Dipeptidyl-Peptidase IV InhibitorsGlucoseProtein HydrolysatesSalmo salarAnimalsDipeptidyl Peptidase 4Fish ProteinsHumansHypoglycemic AgentsDipeptidyl Peptidase 4Dipeptidyl-Peptidase IV InhibitorsFish ProteinsGlucoseHypoglycemic AgentsProtein Hydrolysatesbioactive peptidesDPP-IV inhibitionglucoregulatory peptidesglucose uptakemarine protein hydrolysatemetabolic diseasesalmon protein hydrolysate

Identifiers

PMID38667768
PMCPMC11050766
OpenAlexW4393278709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.