Evidence map›Paper›PMID 38667765›Full record

ArticleMarine drugs2024

Marine-Fungus-Derived Natural Compound 4-Hydroxyphenylacetic Acid Induces Autophagy to Exert Antithrombotic Effects in Zebrafish.

Shaoshuai Xin, Mengqi Zhang, Peihai Li, Lizhen Wang, Xuanming Zhang, Shanshan Zhang, Zhenqiang Mu, Houwen Lin, Xiaobin Li, Kechun Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Antithrombotic Effect ofInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shaoshuai XinBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Mengqi ZhangKey Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs, Key Laboratory of Agro-Products Processing Technology of Shandong Province, Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, 23788 Gongye North Road, Jinan 250100, China.
Peihai LiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Lizhen WangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0003-4743-6939
Xuanming ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0003-1873-1533
Shanshan ZhangBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Zhenqiang MuChongqing Key Laboratory of High Active Traditional Chinese Medicine Delivery System & Chongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing 410331, China.
Houwen LinResearch Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.ORCID 0000-0002-7097-0876
Xiaobin LiBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0002-3775-7694
Kechun LiuBiology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Qilu University of Technology · CNShandong Academy of Agricultural Sciences · CNShanghai Jiao Tong University · CN

Funding

The National Key R&D Program of China ,the Shandong Provincial Natural Science Foundation, the Taishan Scholar Project from Shandong Province to Houwen Lin, and the Jinan Talent Project for University 2022YFC2804100, ZR2021ZD29 and ZR2022MH240, ts20190950, 202228035
6 · The paper itself

Abstract

Marine natural products are important sources of novel drugs. In this study, we isolated 4-hydroxyphenylacetic acid (HPA) from the marine-derived fungus

Indexed as

AutophagyFibrinolytic AgentsPhenylacetatesZebrafishAnimalsAquatic OrganismsBiological ProductsDisease Models, AnimalSignal TransductionThrombosis4-hydroxyphenylacetic acidBiological ProductsFibrinolytic AgentsPhenylacetates4-hydroxyphenylacetic acidantithromboticautophagymarine-derived fungus

Identifiers

PMID38667765
PMCPMC11051058
OpenAlexW4393219133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.