Evidence map›Paper›PMID 38667528›Full record

ArticleDiseases (Basel, Switzerland)2024

Aggressiveness in Italian Children with ADHD: MAOA Gene Polymorphism Involvement.

Ludovico Neri, Beatrice Marziani, Pierluigi Sebastiani, Tiziana Del Beato, Alessia Colanardi, Maria Pia Legge, Anna Aureli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diseases (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ludovico NeriNeurology and Psychiatry Unit for Children and Adolescents, San Salvatore Hospital, via L. Natali, 1, Coppito, 67100 L'Aquila, Italy.
Beatrice MarzianiEmergency Medicine Department, Sant'Anna University Hospital, Via A. Moro, 8, Cona, 44124 Ferrara, Italy.ORCID 0000-0001-5098-3293
Pierluigi SebastianiCNR Institute of Translational Pharmacology, Via Carducci 32, 67100 L'Aquila, Italy.
Tiziana Del BeatoCNR Institute of Translational Pharmacology, Via Carducci 32, 67100 L'Aquila, Italy.
Alessia ColanardiCNR Institute of Translational Pharmacology, Via Carducci 32, 67100 L'Aquila, Italy.
Maria Pia LeggeNeurology and Psychiatry Unit for Children and Adolescents, San Salvatore Hospital, via L. Natali, 1, Coppito, 67100 L'Aquila, Italy.
Anna AureliCNR Institute of Translational Pharmacology, Via Carducci 32, 67100 L'Aquila, Italy.ORCID 0000-0003-3533-4265
Istituto di Farmacologia Traslazionale · ITSan Salvatore Hospital · ITCenter for Orthopaedics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ADHD is a neurodevelopmental disorder that children and adults can develop. A complex interplay of genetic and environmental factors may underlie interindividual variability in ADHD and potentially related aggressive behavior. Using high-resolution molecular biology techniques, we investigated the impact of some MAOA and SLC6A4 variations on ADHD and aggressive behavior in a group of 80 Italian children with ADHD and in 80 healthy controls. We found that homozygous genotypes of MAOA rs6323 and rs1137070 were associated with an increased risk of ADHD (

Indexed as

5-HTTADHDaggressive behaviorMAOA

Identifiers

PMID38667528
PMCPMC11049508
OpenAlexW4393352640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.