Evidence map›Paper›PMID 38667490›Full record

ArticleDiagnostics (Basel, Switzerland)2024

CT Perfusion Derived rCBV < 42% Lesion Volume Is Independently Associated with Followup FLAIR Infarct Volume in Anterior Circulation Large Vessel Occlusion.

Dhairya A Lakhani, Aneri B Balar, Hamza Salim, Manisha Koneru, Sijin Wen, Burak Ozkara, Hanzhang Lu, Richard Wang, Meisam Hoseinyazdi, Risheng Xu and 17 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Perfusion imaging parameters predict long-term clinical outcome in isolated posterior cerebral artery occlusion stroke patients.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 8 institutions in 2 countries.

Dhairya A LakhaniDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0001-7577-1887
Aneri B BalarDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0002-3592-708X
Hamza SalimDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0002-5208-8425
Manisha KoneruCooper Medical School, Rowan University, Camden, NJ 08103, USA.
Sijin WenDepartment of Biostatistics, West Virginia University, Morgantown, WV 26506, USA.
Burak OzkaraDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0002-8769-3342
Hanzhang LuDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Richard WangDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0003-3442-0559
Meisam HoseinyazdiDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0002-4051-2946
Risheng XuDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Mehreen NabiDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Ishan MazumdarDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Andrew ChoDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0001-9109-2294
Kevin ChenDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Sadra SepehriDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Nathan HysonDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Victor UrrutiaDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Licia LunaDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.
Argye E HillisDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21218, USA.ORCID 0000-0002-5192-1171
Jeremy J HeitDepartment of Neurology, Stanford University, Stanford, CA 94305, USA.
Greg W AlbersDepartment of Neurology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-0263-4632
Ansaar T RaiDepartment of Neuroradiology, West Virginia University, Morgantown, WV 26506, USA.
Adam A DmytriwDepartment of Radiology, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-0131-5699
Tobias D FaizyDepartment of Radiology, Neuroendovascular Division, University Medical Center Münster, 48149 Münster, Germany.ORCID 0000-0002-1631-2020
Max WintermarkDepartment of Neuroradiology, MD Anderson Medical Center, Houston, TX 77030, USA.
Kambiz NaelDivision of Neuroradiology, Department of Radiology, University of California San Francisco (UCSF), San Francisco, CA 94143, USA.ORCID 0000-0002-4194-9488
Vivek S YedavalliDepartment of Radiology and Radiological Sciences, Johns Hopkins University, 600 N. Wolfe St., Phipps B100, Baltimore, MD 21287, USA.ORCID 0000-0002-2450-4014
Johns Hopkins University · USStanford University · USWest Virginia University · USCooper Medical School of Rowan University · USHarvard University · USThe University of Texas MD Anderson Cancer Center · USUniversity Hospital Münster · DEUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pretreatment CT Perfusion (CTP) parameter rCBV < 42% lesion volume has recently been shown to predict 90-day mRS. In this study, we aim to assess the relationship between rCBV < 42% and a radiographic follow-up infarct volume delineated on FLAIR images. In this retrospective evaluation of our prospectively collected database, we included acute stroke patients triaged by multimodal CT imaging, including CT angiography and perfusion imaging, with confirmed anterior circulation large vessel occlusion between 9 January 2017 and 10 January 2023. Follow-up FLAIR imaging was used to determine the final infarct volume. Student t, Mann-Whitney-U, and Chi-Square tests were used to assess differences. Spearman's rank correlation and linear regression analysis were used to assess associations between rCBV < 42% and follow-up infarct volume on FLAIR. In total, 158 patients (median age: 68 years, 52.5% female) met our inclusion criteria. rCBV < 42% (ρ = 0.56,

Indexed as

infarct volumerCBV < 42%relative cerebral blood volume

Identifiers

PMID38667490
PMCPMC11049259
OpenAlexW4394962869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.