Evidence map›Paper›PMID 38667187›Full record

ArticleBiosensors2024

A CRISPR/Cas12a-Based System for Sensitive Detection of Antimicrobial-Resistant Genes in Carbapenem-Resistant

Jiyong Shin, Sei Rim Kim, Zifan Xie, Yong-Su Jin, Yi-Cheng Wang

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. [Research Progress on the Application of CRISPR/Cas System in Rapid Testing of Drug-Resistant Bacteria in Clinical Practice].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Review
  3. Review
  4. Article
  5. CRISPR/Cas diagnostics forFrontiers in bioengineering and biotechnology · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Ultrasensitive CRISPR/Cas12a-Based System for Detection ofCurrent issues in molecular biology · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Rapid molecular detection ofFrontiers in bioengineering and biotechnology · 2025
    Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiyong ShinDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.
Sei Rim KimDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.
Zifan XieDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0009-0008-8904-2552
Yong-Su JinDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-4464-9536
Yi-Cheng WangDepartment of Food Science and Human Nutrition, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.

Funding

National Institute of Food and Agriculture ILLU-698-353National Institute of Food and Agriculture ILLU-698-930Royal Society of Chemistry R20-7704
6 · The paper itself

Abstract

Antimicrobial-resistant (AMR) bacteria pose a significant global health threat, and bacteria that produce New Delhi metallo-β-lactamase (NDM) are particularly concerning due to their resistance to most β-lactam antibiotics, including carbapenems. The emergence and spread of NDM-producing genes in food-producing animals highlight the need for a fast and accurate method for detecting AMR bacteria. We therefore propose a PCR-coupled CRISPR/Cas12a-based fluorescence assay that can detect NDM-producing genes (bla

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenemsCRISPR-Associated ProteinsCRISPR-Cas SystemsEndodeoxyribonucleasesAnti-Bacterial AgentsBiosensing TechniquesCarbapenem-Resistant EnterobacteriaceaeDrug Resistance, BacterialEnterobacteriaceaeEscherichia coliAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsCas12a proteinCRISPR-Associated ProteinsEndodeoxyribonucleasesbiosensingfluorescence assayfood safetymulti-drug-resistant bacteriapublic health

Identifiers

PMID38667187
PMCPMC11048238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.