Evidence map›Paper›PMID 38667161›Full record

ArticleBiosensors2024

Enzyme Immobilization by Inkjet Printing on Reagentless Biosensors for Electrochemical Phosphate Detection.

Dongxing Zhang, Yang Bai, Haoran Niu, Lingyun Chen, Junfeng Xiao, Qiuquan Guo, Peipei Jia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dongxing ZhangShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.
Yang BaiDepartment of Biomedical Engineering, Western University, 1151 Richmond Street, London, ON N6A 3K7, Canada.
Haoran NiuShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.
Lingyun ChenShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.
Junfeng XiaoShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.
Qiuquan GuoShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.ORCID 0000-0001-8460-2110
Peipei JiaShenzhen Institute for Advanced Study, University of Electronic Science and Technology of China, Yesun Industry Zone, Guanlan Street, Shenzhen 518110, China.ORCID 0000-0001-7867-8004

Funding

Basic and Applied Basic Research Program of Guangdong Province 2021A1515110880Basic and Applied Basic Research Program of Guangdong Province 2023A1515012752Shenzhen Science and Technology Program JCYJ20210324115412035Shenzhen Science and Technology Program JCYJ20210324122803009Shenzhen Science and Technology Program JCYJ20210324123202008Shenzhen Science and Technology Program ZDSYS20210813095534001
6 · The paper itself

Abstract

Enzyme-based biosensors commonly utilize the drop-casting method for their surface modification. However, the drawbacks of this technique, such as low reproducibility, coffee ring effects, and challenges in mass production, hinder its application. To overcome these limitations, we propose a novel surface functionalization strategy of enzyme crosslinking via inkjet printing for reagentless enzyme-based biosensors. This method includes printing three functional layers onto a screen-printed electrode: the enzyme layer, crosslinking layer, and protective layer. Nanomaterials and substrates are preloaded together during our inkjet printing. Inkjet-printed electrodes feature a uniform enzyme deposition, ensuring high reproducibility and superior electrochemical performance compared to traditional drop-casted ones. The resultant biosensors display high sensitivity, as well as a broad linear response in the physiological range of the serum phosphate. This enzyme crosslinking method has the potential to extend into various enzyme-based biosensors through altering functional layer components.

Indexed as

Biosensing TechniquesElectrochemical TechniquesEnzymes, ImmobilizedPhosphatesElectrodesPrintingReproducibility of ResultsEnzymes, ImmobilizedPhosphatesenzyme immobilizationinkjet printingphosphate detectionreagentless biosensorscreen-printed electrode

Identifiers

PMID38667161
PMCPMC11047959

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.