Evidence map›Paper›PMID 38667018›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Antibiofilm and Immune-Modulatory Activity of Cannabidiol and Cannabigerol in Oral Environments-In Vitro Study.

Hernan Santiago Garzón, Manuela Loaiza-Oliva, María Cecilia Martínez-Pabón, Jenniffer Puerta-Suárez, Mayra Alexandra Téllez Corral, Bruno Bueno-Silva, Daniel R Suárez, David Díaz-Báez, Lina J Suárez

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Efficacy of Cannabidiol in Reducing Virulence ofInternational journal of molecular sciences · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Cannabidiol (CBD) Acts as an Antioxidant onAntibiotics (Basel, Switzerland) · 2025
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Hernan Santiago GarzónPrograma de Doctorado en Ingeniería, Facultad de Ingeniería, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-8320-6220
Manuela Loaiza-OlivaLaboratory of Oral Microbiology, Faculty of Dentistry, University of Antioquia, Medellín 050010, Colombia.ORCID 0000-0001-6839-1982
María Cecilia Martínez-PabónLaboratory of Oral Microbiology, Faculty of Dentistry, University of Antioquia, Medellín 050010, Colombia.ORCID 0000-0002-8115-3089
Jenniffer Puerta-SuárezLaboratory of Oral Microbiology, Faculty of Dentistry, University of Antioquia, Medellín 050010, Colombia.ORCID 0000-0002-9831-5267
Mayra Alexandra Téllez CorralCentro de Investigaciones Odontológicas, Facultad de Odontología, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0003-0006-7822
Bruno Bueno-SilvaDepartment of Periodontology, Dental Research Division, Guarulhos University, Guarulhos 07023-070, Brazil.ORCID 0000-0003-3275-5910
Daniel R SuárezPrograma de Doctorado en Ingeniería, Facultad de Ingeniería, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.ORCID 0000-0001-6264-2250
David Díaz-BáezUnit of Basic Oral Investigation-UIBO, Facultad de Odontología, Universidad El Bosque, Bogotá 11001, Colombia.ORCID 0000-0001-8890-6250
Lina J SuárezCentro de Investigaciones Odontológicas, Departamento del Sistema Periodontal, Facultad de Odontología, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.
Pontificia Universidad Javeriana · COUniversidad de Antioquia · COUniversidade Estadual de Campinas (UNICAMP) · BRUniversidad El Bosque · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the in vitro antimicrobial and antibiofilm properties and the immune modulatory activity of cannabidiol (CBD) and cannabigerol (CBG) on oral bacteria and periodontal ligament fibroblasts (PLF).

methodsCytotoxicity was assessed by propidium iodide flow cytometry on fibroblasts derived from the periodontal ligament. The minimum inhibitory concentration (MIC) of CBD and CBG for

resultsCBD-treated cell viability was greater than 95%, and for CBG, it was higher than 88%. MIC for

conclusionBoth CBG and CBD inhibit

Indexed as

antimicrobial agentscannabidiolcannabigerolcannabinoidsimmunomodulationoral biofilmsperiodontitis

Identifiers

PMID38667018
PMCPMC11047394
OpenAlexW4394613858

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.