Evidence map›Paper›PMID 38666643›Full record

ArticleInflammatory bowel diseases2025

Variation Between Hospitals in Outcomes and Costs of IBD Care: Results From the IBD Value Study.

Reinier C A van Linschoten, C Janneke van der Woude, Elyke Visser, Nikki van Leeuwen, Alexander G L Bodelier, Claire Fitzpatrick, Vincent de Jonge, Hestia Vermeulen, K Evelyne Verweij, Sanne van der Wiel and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Inflammatory bowel diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Reinier C A van LinschotenDepartment of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands.ORCID 0000-0003-3052-596X
C Janneke van der WoudeDepartment of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, the Netherlands.
Elyke VisserDepartment of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands.
Nikki van LeeuwenDepartment of Public Health, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Alexander G L BodelierDepartment of Gastroenterology and Hepatology, Amphia Hospital, Breda, the Netherlands.
Claire FitzpatrickDepartment of Gastroenterology and Hepatology, IJsselland Hospital, Capelle aan de IJssel, the Netherlands.
Vincent de JongeDepartment of Gastroenterology and Hepatology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.
Hestia VermeulenDepartment of Gastroenterology and Hepatology, Ikazia Hospital, Rotterdam, the Netherlands.
K Evelyne VerweijDepartment of Gastroenterology and Hepatology, Maasstad Hospital, Rotterdam, the Netherlands.
Sanne van der WielDepartment of Gastroenterology and Hepatology, Reinier de Graaf Gasthuis, Delft, the Netherlands.
Daan NieboerDepartment of Public Health, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Erwin BirnieDepartment of Statistics and Education, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands.
Daniëlle van der HorstCrohn & Colitis NL, Woerden, the Netherlands.
Jan A HazelzetDepartment of Public Health, Erasmus University Medical Centre, Rotterdam, the Netherlands.
Desirée van NoordDepartment of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands.
Rachel L WestDepartment of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Rotterdam, the Netherlands.

Funding

Franciscus Research FoundationResearch and Development Foundation
6 · The paper itself

Abstract

backgroundData on variation in outcomes and costs of the treatment of inflammatory bowel disease (IBD) can be used to identify areas for cost and quality improvement. It can also help healthcare providers learn from each other and strive for equity in care. We aimed to assess the variation in outcomes and costs of IBD care between hospitals.

methodsWe conducted a 12-month cohort study in 8 hospitals in the Netherlands. Patients with IBD who were treated with biologics and new small molecules were included. The percentage of variation in outcomes (following the International Consortium for Health Outcomes Measurement standard set) and costs attributable to the treating hospital were analyzed with intraclass correlation coefficients (ICCs) from case mix-adjusted (generalized) linear mixed models.

resultsWe included 1010 patients (median age 45 years, 55% female). Clinicians reported high remission rates (83%), while patient-reported rates were lower (40%). During the 12-month follow-up, 5.2% of patients used prednisolone for more than 3 months. Hospital costs (outpatient, inpatient, and medication costs) were substantial (median: €8323 per 6 months), mainly attributed to advanced therapies (€6611). Most of the variation in outcomes and costs among patients could not be attributed to the treating hospitals, with ICCs typically between 0% and 2%. Instead, patient-level characteristics, often with ICCs above 50%, accounted for these variations.

conclusionsVariation in outcomes and costs cannot be used to differentiate between hospitals for quality of care. Future quality improvement initiatives should look at differences in structure and process measures of care and implement patient-level interventions to improve quality of IBD care. TRIAL REGISTRATION NUMBER: NL8276.

Indexed as

Biological ProductsHealth Care CostsHospital CostsHospitalsInflammatory Bowel DiseasesAdultAgedCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedNetherlandsBiological Productsadvanced therapyinflammatory bowel diseasequality improvementvalue-based healthcarevariation

Identifiers

PMID38666643
PMCPMC11808576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.