Evidence map›Paper›PMID 38666640›Full record

ArticleEmerging infectious diseases2024

Protective Efficacy of Lyophilized Vesicular Stomatitis Virus-Based Vaccines in Animal Model.

Abd'jeleel Salawudeen, Geoff Soule, Nikesh Tailor, Levi Klassen, Jonathan Audet, Angela Sloan, Yvon Deschambault, David Safronetz

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Emerging infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Abd'jeleel Salawudeen
Geoff Soule
Nikesh Tailor
Levi Klassen
Jonathan Audet
Angela Sloan
Yvon Deschambault
David Safronetz
University of Manitoba · CAPublic Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus-based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicular stomatitis virus-based vaccines will each require extensive analysis to optimize stabilizing formulations.

Indexed as

Disease Models, AnimalFreeze DryingVesicular StomatitisViral VaccinesAnimalsAntibodies, ViralGuinea PigsVaccine EfficacyVesicular stomatitis Indiana virusVesiculovirusAntibodies, ViralViral Vaccinesanimal modelsEbola virusglycoproteinsguinea pigsLassa viruslyophilizedvaccinesvesicular stomatitis virusviruseszoonoses

Identifiers

PMID38666640
PMCPMC11060439
OpenAlexW4395448924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.