ReviewEmerging infectious diseases2024
Crimean Congo Hemorrhagic Fever Virus for Clinicians-Virology, Pathogenesis, and Pathology.
Review in Emerging infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 21 citations in OpenAlex.
- Pathogenicity and virulence of Crimean-Congo hemorrhagic fever virus: From enzootic maintenance to severe human disease.Virulence · 2026Review
- Dual-antigen AdV5 vaccines against Crimean-Congo hemorrhagic fever virus induce superior humoral and Th1-biased cellular immunity.Scientific reports · 2026Article
- Drivers of Viral Spillover: An Examination of How Pathogens Spread.Pathogens (Basel, Switzerland) · 2026Review
- Loss of type I interferon signaling in Kupffer cells triggers viral spread and fatal liver damage in a mouse model of Crimean-Congo hemorrhagic fever.PLoS pathogens · 2026Article
- Diagnostic performance of clinical symptom combinations for Crimean-Congo hemorrhagic fever in emergency department patients with reported arthropod bites, stings, or exposure.Tropical medicine and health · 2026Article
- Nairobi sheep disease virus: an emerging threat with unresolved pathogenesis and zoonotic potential.Journal of virology · 2026Review
- Field vaccination against CCHFV and Hyalomma tick infestation reduces multiple tick-borne infections in sheep.NPJ vaccines · 2026Article
- Integrated surveillance, virus isolation and phylogenetic characterization of Crimean-Congo hemorrhagic fever virus in Central Kazakhstan.Frontiers in veterinary science · 2026Article
- Microbiological perspectives on Crimean-Congo hemorrhagic fever: Seroprevalence and viral pathogenesis in Iraq.Biotechnology notes (Amsterdam, Netherlands) · 2026Article
- Longitudinal seroprevalence of Crimean-Congo hemorrhagic fever virus in Southern Uganda.Emerging microbes & infections · 2025Article
- Crimean-Congo Hemorrhagic Fever Virus in Cattle and Ticks, Israel.Emerging infectious diseases · 2025Article
- Prognostic Significance of CRP/Albumin, D-Dimer/Albumin, D-Dimer/Fibrinogen Ratios and Triglyceride-Glucose Index in Crimean-Congo Hemorrhagic Fever: A Prospective Observational Study.Tropical medicine and infectious disease · 2025Article
- Molecular and Clinical Characterization of Crimean-Congo Hemorrhagic Fever in Bulgaria, 2015-2024.Pathogens (Basel, Switzerland) · 2025Article
- Review
- Neonatal mouse model reveals pathogenesis of Shanxi Tick Virus 2 isolated from Haemaphysalis longicornis.Virology journal · 2025Article
- Crimean-Congo hemorrhagic fever: Pathogenesis, transmission and public health challenges.World journal of virology · 2025Review
- Two Human Infections with Diverse Europe-1 Crimean-Congo Hemorrhagic Fever Virus Strains, North Macedonia, 2024.Emerging infectious diseases · 2025Article
- Crimean-Congo Hemorrhagic Fever Mimicking HELLP Syndrome in a Pregnant Woman and Her Infant in Kosovo: A Case Report.Viruses · 2025Article
- Crimean-Congo Hemorrhagic Fever Virus for Clinicians-Epidemiology, Clinical Manifestations, and Prevention.Emerging infectious diseases · 2024Review
- Crimean-Congo Hemorrhagic Fever Virus for Clinicians-Diagnosis, Clinical Management, and Therapeutics.Emerging infectious diseases · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crimean-Congo hemorrhagic fever (CCHF), caused by CCHF virus, is a tickborne disease that can cause a range of illness outcomes, from asymptomatic infection to fatal viral hemorrhagic fever; the disease has been described in >30 countries. We conducted a literature review to provide an overview of the virology, pathogenesis, and pathology of CCHF for clinicians. The virus life cycle and molecular interactions are complex and not fully described. Although pathogenesis and immunobiology are not yet fully understood, it is clear that multiple processes contribute to viral entry, replication, and pathological damage. Limited autopsy reports describe multiorgan involvement with extravasation and hemorrhages. Advanced understanding of CCHF virus pathogenesis and immunology will improve patient care and accelerate the development of medical countermeasures for CCHF.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.