Evidence map›Paper›PMID 38666408›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Bictegravir Use During Pregnancy: A Multicenter Retrospective Analysis Evaluating HIV Viral Suppression and Perinatal Outcomes.

Lauren M Holt, William R Short, Florence Momplaisir, Eleanor Hyun, Jennifer McKinney, Andrea Lugo Morales, Alejandra Duque, Brian Druyan, Chima Ndubizu, Luthita Duthely and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Lauren M HoltDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0009-0006-8428-3643
William R ShortDepartment of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Florence MomplaisirDepartment of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Eleanor HyunUniversity of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Jennifer McKinneyDepartment of Gynecology and Obstetrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-1641-9610
Andrea Lugo MoralesDepartment of Gynecology and Obstetrics, Baylor College of Medicine, Houston, Texas, USA.
Alejandra DuqueBaylor College of Medicine, Houston, Texas, USA.
Brian DruyanDepartment of Gynecology and Obstetrics, University of Miami School of Medicine, Miami, Florida, USA.
Chima NdubizuDepartment of Gynecology and Obstetrics, University of Miami School of Medicine, Miami, Florida, USA.
Luthita DuthelyUniversity of Miami School of Medicine, Miami, Florida, USA.
Naima JosephDepartment of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, USA.
Anandi N ShethDepartment of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Martina L BadellDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Baylor College of Medicine · USEmory University · USUniversity of Miami · USUniversity of Pennsylvania · USBoston University · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Savita Pahwa · 2007 to 2026
$33.8M
The University of Miami AIDS Research Center on Mental Health and HIV/AIDS - Center for HIV & Research in Mental Health (CHARM)Research Core & MHD-CEP30MH133399 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI Victoria Behar-Zusman · 2023 to 2026
$8.9M
University of Miami Developmental HIV/AIDS Mental Health Research Center (D-ARC)P30MH116867 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2019 to 2023
$6.5M
Substance Use and HIV Prevention Research in Minority Communities Training ProgramR25DA028567 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Julia Lechuga, Torsten Brian Neilands · 2009 to 2026
$5.4M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
mCARES: An HIV Adherence Intervention to Support Racial/Ethnic Minority Women with/at-risk of Substance Use and Mental Health DisordersR34DA057150 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI DUTHELY, LUNTHITA M · 2022 to 2024
$690k
NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI073961NIDA NIH HHS R25 DA028567NIDA NIH HHS R34 DA057150NIMH NIH HHS P30 MH116867NIMH NIH HHS P30 MH133399NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

This study describes the largest cohort to date (n = 147) of pregnant patients with human immunodeficiency virus (HIV) on bictegravir (BIC). BIC in pregnancy was associated with high levels of viral suppression and perinatal outcomes similar to those in the published literature. These findings support consideration for the use of BIC in managing HIV during pregnancy.

Indexed as

Heterocyclic Compounds, 3-RingHIV InfectionsPregnancy Complications, InfectiousViral LoadAdultAmidesAnti-HIV AgentsFemaleHeterocyclic Compounds, 4 or More RingsHumansInfant, NewbornInfectious Disease Transmission, VerticalPiperazinesPregnancyPregnancy OutcomePyridonesAmidesAnti-HIV AgentsbictegravirHeterocyclic Compounds, 3-RingHeterocyclic Compounds, 4 or More RingsPiperazinesPyridonesBiktarvyHIVperinatal outcomespregnancy

Identifiers

PMID38666408
PMCPMC12098006
OpenAlexW4395674302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.