Evidence map›Paper›PMID 38666049›Full record

ArticleBone reports2024

Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice.

Irina L Tourkova, Quitterie C Larrouture, Silvia Liu, Jianhua Luo, Katherine E Shipman, Kelechi M Onwuka, Ora A Weisz, Vladimir Riazanski, Deborah J Nelson, Matthew L MacDonald and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bone reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Irina L TourkovaDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Quitterie C LarroutureDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Silvia LiuDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Jianhua LuoDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Katherine E ShipmanRenal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kelechi M OnwukaDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
Ora A WeiszRenal Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Vladimir RiazanskiDept of Neurobiology, Pharmacology & Physiology, University of Chicago, Chicago, IL, USA.
Deborah J NelsonDept of Neurobiology, Pharmacology & Physiology, University of Chicago, Chicago, IL, USA.
Matthew L MacDonaldDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Paul H SchlesingerDepartment of Cell Biology, Washington University, St. Louis, MO, USA.
Harry C BlairDepartment of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
University of Pittsburgh · USUniversity of Chicago · USVA Pittsburgh Healthcare System · USWashington University in St. Louis · US

Funding

T32 Research Training in Diabetes and EndocrinologyT32DK007052 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROBERT M O'DOHERTY · 1986 to 2026
$6.3M
Endocytic Pathway Dysfunction in Dent DiseaseR01DK125049 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WEISZ, ORA A · 2020 to 2024
$2.3M
NIDDK NIH HHS R01 DK125049NIDDK NIH HHS T32 DK007052
6 · The paper itself

Abstract

Acid transport is required for bone synthesis by osteoblasts. The osteoblast basolateral surface extrudes acid by Na

Indexed as

Bone formation rateClC3ClC5Mineral transport

Identifiers

PMID38666049
PMCPMC11043850
OpenAlexW4394858037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.