Evidence map›Paper›PMID 38665901›Full record

ArticleProceedings. IEEE Symposium on Security and Privacy2023

Scalable and Privacy-Preserving Federated Principal Component Analysis.

David Froelicher, Hyunghoon Cho, Manaswitha Edupalli, Joao Sa Sousa, Jean-Philippe Bossuat, Apostolos Pyrgelis, Juan R Troncoso-Pastoriza, Bonnie Berger, Jean-Pierre Hubaux

Abstract read
In one paragraph

Article in Proceedings. IEEE Symposium on Security and Privacy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Privacy-Enhancing Technologies in Biomedical Data Science.Annual review of biomedical data science · 2024
    Review
  6. Article
  7. Article
  8. Scalable and Privacy-Preserving Federated Principal Component Analysis.Proceedings. IEEE Symposium on Security and Privacy · 2023
    Article
  9. Secure Discovery of Genetic Relatives across Large-Scale and Distributed Genomic Datasets.Research in computational molecular biology : ... Annual International Conference, RECOMB ... : proceedings. RECOMB (Conference : 2005- )
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David FroelicherMIT.
Hyunghoon ChoBroad Institute of MIT and Harvard.
Manaswitha EdupalliBroad Institute of MIT and Harvard.
Joao Sa SousaEPFL.
Jean-Philippe BossuatTune Insight SA.
Apostolos PyrgelisEPFL.
Juan R Troncoso-PastorizaTune Insight SA.
Bonnie BergerMIT.
Jean-Pierre HubauxEPFL.

Funding

Genetic & Social Determinants of Health: Center for Admixture Science and TechnologyRM1HG011558 · NHGRI · YALE UNIVERSITY · PI FRAZER, KELLY A, GYMREK, MELISSA · 2021 to 2025
$11.2M
Privacy-preserving genomic medicine at scaleR01HG010959 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BERGER, BONNIE · 2020 to 2023
$2.6M
Computational Methods for Enhancing Privacy in Biomedical Data SharingDP5OD029574 · OD · YALE UNIVERSITY · PI CHO, HYUNGHOON · 2020 to 2024
$2.0M
NHGRI NIH HHS R01 HG010959NHGRI NIH HHS RM1 HG011558NIH HHS DP5 OD029574
6 · The paper itself

Abstract

Principal component analysis (PCA) is an essential algorithm for dimensionality reduction in many data science domains. We address the problem of performing a federated PCA on private data distributed among multiple data providers while ensuring data confidentiality. Our solution, SF-PCA, is an end-to-end secure system that preserves the confidentiality of both the original data and all intermediate results in a passive-adversary model with up to all-but-one colluding parties. SF-PCA jointly leverages multiparty homomorphic encryption, interactive protocols, and edge computing to efficiently interleave computations on local cleartext data with operations on collectively encrypted data. SF-PCA obtains results as accurate as non-secure centralized solutions, independently of the data distribution among the parties. It scales linearly or better with the dataset dimensions and with the number of data providers. SF-PCA is more precise than existing approaches that approximate the solution by combining local analysis results, and between 3x and 250x faster than privacy-preserving alternatives based solely on secure multiparty computation or homomorphic encryption. Our work demonstrates the practical applicability of secure and federated PCA on private distributed datasets.

Identifiers

PMID38665901
PMCPMC11044025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.