Evidence map›Paper›PMID 38665775›Full record

ArticleOptica2023

Tian Xia, Kohei Umezu, Deirdre M Scully, Shang Wang, Irina V Larina

Open access · goldAbstract read
In one paragraph

Article in Optica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Biomedical optics express · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Research progress in the role of tubal ciliary movement in female infertility-related disorders.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tian XiaDepartment of Integrative Physiology, Baylor College of Medicine, Houston, Texas 77030, USA.ORCID 0000-0003-2985-6489
Kohei UmezuDepartment of Integrative Physiology, Baylor College of Medicine, Houston, Texas 77030, USA.ORCID 0000-0002-4225-9817
Deirdre M ScullyDepartment of Integrative Physiology, Baylor College of Medicine, Houston, Texas 77030, USA.
Shang WangDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey 07030, USA.ORCID 0000-0001-9447-719X
Irina V LarinaDepartment of Integrative Physiology, Baylor College of Medicine, Houston, Texas 77030, USA.ORCID 0000-0002-1571-2997
Baylor College of Medicine · USStevens Institute of Technology · US

Funding

Biomechanics of early mammalian cardiogenesisR01HD096335 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LARINA, IRINA · 2018 to 2022
$2.8M
In vivo analysis of mammalian fertilizationR01EB027099 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI LARINA, IRINA · 2019 to 2022
$2.5M
Multi-contrast dynamic optical imaging to advance live developmental biologyR35GM142953 · NIGMS · THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY · PI WANG, SHANG · 2021 to 2025
$1.9M
In vivo investigation of cilia function in the fallopian tubeR01HD112102 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Irina Larina · 2024 to 2026
$1.8M
In vivo investigation of fallopian tube transportF32HD110222 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI SCULLY, DEIRDRE · 2022 to 2023
$92k
NIBIB NIH HHS R01 EB027099NICHD NIH HHS F32 HD110222NICHD NIH HHS R01 HD096335NICHD NIH HHS R01 HD112102NIGMS NIH HHS R35 GM142953
6 · The paper itself

Abstract

Motile cilia are dynamic hair-like structures covering epithelial surfaces in multiple organs. The periodic coordinated beating of cilia creates waves propagating along the surface, known as the metachronal waves, which transport fluids and mucus along the epithelium. Motile ciliopathies result from disrupted coordinated cilia beating and are associated with serious clinical complications, including reproductive disorders. Despite the recognized clinical significance, research of cilia dynamics is extremely limited. Here, we present quantitative imaging of cilia metachronal waves volumetrically through tissue layers using dynamic optical coherence tomography (OCT). Our method relies on spatiotemporal mapping of the phase of intensity fluctuations in OCT images caused by the ciliary beating. We validated our new method

Identifiers

PMID38665775
PMCPMC11044847
OpenAlexW4386954528

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.