Evidence map›Paper›PMID 38665311›Full record

ArticleAdvanced nanobiomed research2024

Plant-Derived Zein as an Alternative to Animal-Derived Gelatin for Use as a Tissue Engineering Scaffold.

Apurva Limaye, Venkatesan Perumal, Courtney M Karner, Treena Livingston Arinzeh

Open access · goldAbstract read
In one paragraph

Article in Advanced nanobiomed research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Apurva LimayeDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Venkatesan PerumalDepartment of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA.
Courtney M KarnerDepartment of Internal Medicine, Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Treena Livingston ArinzehDepartment of Biomedical Engineering, Columbia University, 3960 Broadway, New York, NY 10027, USA.
New Jersey Institute of Technology · USColumbia University · USSouthwestern Medical Center · US

Funding

A Metabolic Strategy Utilizing a Zein Scaffold for Bone RepairR21AR078399 · NIAMS · NEW JERSEY INSTITUTE OF TECHNOLOGY · PI ARINZEH, TREENA LYNNE · 2021 to 2022
$400k
NIAMS NIH HHS R21 AR078399
6 · The paper itself

Abstract

Natural biomaterials are commonly used as tissue engineering scaffolds due to their biocompatibility and biodegradability. Plant-derived materials have also gained significant interest due to their abundance and as a sustainable resource. This study evaluates the corn-derived protein zein as a plant-derived substitute for animal-derived gelatin, which is widely used for its favorable cell adhesion properties. Limited studies exist evaluating pure zein for tissue engineering. Herein, fibrous zein scaffolds are evaluated in vitro for cell adhesion, growth, and infiltration into the scaffold in comparison to gelatin scaffolds and are further studied in a subcutaneous model in vivo. Human mesenchymal stem cells (MSCs) on zein scaffolds express focal adhesion kinase and integrins such as

Indexed as

electrospinninggelatinmesenchymal stem cellstissue engineeringzein

Identifiers

PMID38665311
PMCPMC11045004
OpenAlexW4390144321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.