Evidence map›Paper›PMID 38665170›Full record

ArticleOpen forum infectious diseases2024

Risk of Invasive Meningococcal Disease in Preterm Infants.

Anna Calvert, Helen Campbell, Paul T Heath, Christine E Jones, Kirsty Le Doare, Anna Mensah, Shamez Ladhani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Anna CalvertCentre for Neonatal and Paediatric Infection and Vaccine Institute, St George's, University of London, London, UK.ORCID https://orcid.org/0000-0002-1922-6208
Helen CampbellImmunisation and Countermeasures Division, UK Health Security Agency, London, UK.ORCID https://orcid.org/0000-0001-9840-8917
Paul T HeathCentre for Neonatal and Paediatric Infection and Vaccine Institute, St George's, University of London, London, UK.
Christine E JonesNIHR Southampton Clinical Research Facility and Biomedical Research Centre, Southampton, UK.
Kirsty Le DoareCentre for Neonatal and Paediatric Infection and Vaccine Institute, St George's, University of London, London, UK.
Anna MensahImmunisation and Countermeasures Division, UK Health Security Agency, London, UK.
Shamez LadhaniCentre for Neonatal and Paediatric Infection and Vaccine Institute, St George's, University of London, London, UK.
St George's, University of London · GBUK Health Security Agency · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Invasive meningococcal disease (IMD) is most common in the first year of life. We hypothesized that preterm infants may have a higher risk of IMD and more severe disease than term infants. We compared the incidence, demographics, clinical presentation, and outcomes of IMD in preterm compared with term infants during the first 5 years after implementation of a national meningococcal group B vaccine (4CMenB) for infants in England. Methods: The UK Health Security Agency conducts enhanced national IMD surveillance with detailed follow-up of all confirmed cases in England. Infants aged <1 year (uncorrected for gestational age) with IMD confirmed between 1 September 2015 and 31 August 2020 were included. Results: There were 393 infant IMD cases (incidence, 12.4/100 000 live births). Among 363 (92.4%) of the infants with known gestational age, the IMD incidence was higher in preterm (<37 weeks' gestation) than in term infants (18.3/100 000 vs 10.9/100 000; incidence rate ratio [IRR], 1.68 [95% confidence interval, 1.23-2.29]; Conclusions: Preterm infants had a higher incidence of IMD than term infants and the IMD incidence was highest in infants born at <32 weeks' gestation. Preterm infants also had a higher risk of IMD sequelae.

Indexed as

epidemiologyMeningococcuspreterm

Identifiers

PMID38665170
PMCPMC11045171
OpenAlexW4394822195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.