ArticleJournal of global health2024
A causal relationship between educational attainment and risk of infectious diseases: A Mendelian randomisation study.
Article in Journal of global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The links between adolescent health and education: pathways, impacts and economic modelling.Health policy and planning · 2026Article
- Healthcare inequalities in general practice due to educational level: A retrospective cohort study analysing patients' presentation and GP response to requests.The European journal of general practice · 2026Article
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- Risk factors and outcomes of healthcare-associated infections in a Brazilian intensive care unit: A cross-sectional study.Belitung nursing journal · 2026Article
- Study on the spatial-temporal evolution and influencing factors of AIDS incidence in China from 2006 to 2022.BMC infectious diseases · 2025Article
- Causal effect of education on low back pain, intervertebral disc degeneration and sciatica: Mendelian randomization study.Future science OA · 2025Article
- Early-Life Infections, Antibiotics and Later Risk of Childhood and Early Adult-Onset Inflammatory Bowel Disease: Pooled Analysis of Two Scandinavian Birth Cohorts.Alimentary pharmacology & therapeutics · 2025Article
- Assessing the Impact of Frailty on Infection Risk in Older Adults: Prospective Observational Cohort Study.JMIR public health and surveillance · 2024Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
Background: Previous observational studies have investigated the association between educational attainment and sepsis, pneumonia, and urinary tract infections (UTIs). However, their findings have been susceptible to reverse causality and confounding factors. Furthermore, no study has examined the effect of educational level on the risk of infections of the skin and subcutaneous tissue (SSTIs). Thus, we aimed to evaluate the causal relationships between educational level and the risk of four infectious diseases using Mendelian randomisation (MR) techniques. Methods: We used univariable MR analysis to investigate the causal associations between educational attainment (years of schooling (n = 766 345) and holding college or university degree (n = 334 070)) and four infectious diseases (sepsis (n = 486 484), pneumonia (n = 486 484), UTIs (n = 463 010), and SSTIs (n = 218 792)). We included genetic instrumental variables with a genome-wide significance (P < 5 × 10 Results: Genetically predicted years of schooling were associated with a reduced risk of sepsis (odds ratio (OR) = 0.763; 95% confidence interval (CI) = 0.668-0.870, P = 5.525 × 10 Conclusions: Our findings suggest that increased educational attainment may be causally associated with a decreased risk of sepsis, pneumonia, UTIs, and SSTIs.
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