Evidence map›Paper›PMID 38664995›Full record

ReviewMolecular microbiology2024

House of CarDs: Functional insights into the transcriptional regulator CdnL.

Erika L Smith, Erin D Goley

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Erika L SmithDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Erin D GoleyDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-8518-2303
Johns Hopkins University · US

Funding

Biochemistry, Cellular and Molecular Biology Program: JHU BioGREAT (Biomedical Graduate REsiliency & Adaptability Training)T32GM144272 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Takanari Inoue · 2022 to 2026
$5.4M
Local and global regulation of bacterial growthR35GM136221 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Erin D Goley · 2020 to 2026
$3.0M
NIGMS NIH HHS R35 GM136221NIGMS NIH HHS R35GM136221NIGMS NIH HHS T32 GM144272NIGMS NIH HHS T32GM144272
6 · The paper itself

Abstract

Regulation of bacterial transcription is a complex and multi-faceted phenomenon that is critical for growth and adaptation. Proteins in the CarD_CdnL_TRCF family are widespread, often essential, regulators of transcription of genes required for growth and metabolic homeostasis. Research in the last decade has described the mechanistic and structural bases of CarD-CdnL-mediated regulation of transcription initiation. More recently, studies in a range of bacteria have begun to elucidate the physiological roles of CarD-CdnL proteins as well as mechanisms by which these proteins, themselves, are regulated. A theme has emerged wherein regulation of CarD-CdnL proteins is central to bacterial adaptation to stress and/or changing environmental conditions.

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialBacteriaTranscription FactorsTranscription, GeneticBacterial ProteinsTranscription Factorsbacterial adaptationCarDCdnLstress responsetranscription

Identifiers

PMID38664995
PMCPMC11502505
OpenAlexW4395677915

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.