Evidence map›Paper›PMID 38664852›Full record

ArticleJournal of orthopaedic surgery and research2024

Investigating the impact of cartilaginous endplate herniation on recovery from percutaneous endoscopic lumbar discectomy.

Zenghui Zhao, Hao Qi, Chenchen Wang, Anqi Zhao, Feiyu Zu, Jianzhou Zhang, Mengzi He, Hongru Yuan, Ao Yang, Chenxi Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Minor endplate damage as an initiator of systemic biomechanical disruption of the lumbar disc: a finite element analysis of the 'mechanical tipping point' in disc failure.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Risk Factor Analysis of Residual Low Back Pain After Unilateral Biportal Endoscopic Discectomy in Patients With Lumbar Disc Herniation.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Zenghui Zhao *Department of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Hao Qi *Department of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Chenchen WangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Anqi ZhaoHebei Medical University School of Basic Medical Sciences, Shijiazhuang, China.
Feiyu ZuDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Jianzhou ZhangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Mengzi HeDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Hongru YuanDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Ao YangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Chenxi WangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Di ZhangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China. 38300320@hebmu.edu.cn.
Hebei Medical University · CNThird Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the influence of herniation of cartilaginous endplates on postoperative pain and functional recovery in patients undergoing percutaneous endoscopic lumbar discectomy (PELD) for lumbar disc herniation (LDH).

methodsA retrospective analysis was conducted on 126 patients with LDH treated with PELD at the Third Hospital of Hebei Medical University from January 2021 to January 2022. Whether cartilaginous endplates had herniated was identified by analyzing these specific findings from MRI scans: posterior marginal nodes, posterior osteophytes, mid endplate irregularities, heterogeneous low signal intensity of extruded material, and Modic changes in posterior corners and mid endplates. Patients were assessed for postoperative pain using the Visual Analogue Scale (VAS) and functional recovery using the Oswestry Disability Index (ODI) and Modified MacNab criteria. Statistical analyses compared outcomes based on the presence of herniation of cartilaginous endplates.

resultsPatients with herniation of cartilaginous endplates experienced higher pain scores early postoperatively but showed significant improvement in pain and functional status over the long term. The back pain VAS scores showed significant differences between the groups with and without herniation of cartilaginous endplates on postoperative day 1 and 1 month (P < 0.05). Leg pain VAS scores showed significant differences on postoperative day 1 (P < 0.05). Modic changes were significantly associated with variations in postoperative recovery, highlighting their importance in predicting patient outcomes. In patients with herniation of cartilaginous endplates, there were statistically significant differences in the back pain VAS scores at 1 month postoperatively and the ODI functional scores on postoperative day 1 between the groups with and without Modic changes (P < 0.05). There were no significant differences in the surgical outcomes between patients with and without these conditions regarding the Modified MacNab criteria (P > 0.05).

conclusionHerniation of cartilaginous endplates significantly affect early postoperative pain and functional recovery in LDH patients undergoing PELD. These findings emphasize the need for clinical consideration of these imaging features in the preoperative planning and postoperative management to enhance patient outcomes and satisfaction.

Indexed as

Diskectomy, PercutaneousEndoscopyIntervertebral Disc DisplacementLumbar VertebraeRecovery of FunctionAdultAgedCartilageFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPain MeasurementPostoperative PainRetrospective StudiesHerniation of cartilaginous endplatesLumbar disc herniation (LDH)Modic changesPercutaneous endoscopic lumbar discectomy (PELD)Postoperative pain

Identifiers

PMID38664852
PMCPMC11044348
OpenAlexW4395463822

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.