Evidence map›Paper›PMID 38664829›Full record

ArticleParasites & vectors2024

Assessment of the in vitro acaricidal activity of Bravecto

Kotaro Takano, Scott Carver, Yolandi Vermaak, Katja Fischer, Robert J Harvey, Kate E Mounsey

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Kotaro TakanoSchool of Health, University of the Sunshine Coast, Maroochydore, QLD, Australia.
Scott CarverOdum School of Ecology, University of Georgia, Georgia, USA.
Yolandi VermaakWombat Support and Rescue NSW/ACT Inc., Australian Capital Territory, Canberra, Australia.
Katja FischerInfection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Robert J HarveySchool of Health, University of the Sunshine Coast, Maroochydore, QLD, Australia.
Kate E MounseySchool of Health, University of the Sunshine Coast, Maroochydore, QLD, Australia. kmounsey@usc.edu.au.
University of the Sunshine Coast · AUACT GovernmentQIMR Berghofer Medical Research Institute · AUUniversity of Georgia · US

Funding

Australian Research Council LP180101251
6 · The paper itself

Abstract

backgroundSarcoptic mange is a serious animal welfare concern in bare-nosed wombats (Vombatus ursinus). Fluralaner (Bravecto

methodsSarcoptes scabiei were sourced from experimentally infested pigs. In vitro assays were performed to determine the lethal concentration (LC

resultsAll compounds were highly effective at killing mites in vitro. The LC

conclusionsThese results confirm the acaricidal properties of Bravecto, demonstrate acaricidal properties of Orange Power and support the potential suitability of Orange Power and its active constituents as a diluent for Bravecto. As well as killing mites via direct exposure, Orange Power could potentially enhance the topical delivery of Bravecto to wombats by increasing drug penetration in hyperkeratotic crusts. Further research evaluating the physiochemical properties and modes of action of Orange Power and its constituents as a formulation vehicle would be of value.

Indexed as

AcaricidesIsoxazolesPlant OilsSarcoptes scabieiScabiesAcyclic MonoterpenesAnimalsCyclohexenesLethal Dose 50LimoneneSwineTerpenesA1443 compoundAcaricidesAcyclic MonoterpenescitralCyclohexenesIsoxazolesLimoneneorange oilPlant OilsTerpenesBare-nosed wombatCitrus oilEssential oilFluralanerSarcoptes scabieiSarcoptic mangeScabiesVombatus ursinus

Identifiers

PMID38664829
PMCPMC11046784
OpenAlexW4395467436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.