Evidence map›Paper›PMID 38664580›Full record

ArticleCommunications biology2024

The dual coding of a single sex pheromone receptor in Asian honeybee Apis cerana.

Haoqin Ke, Jonathan D Bohbot, Yongjuan Chi, Shiwen Duan, Xiaomei Ma, Bingzhong Ren, Yinliang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Haoqin Ke *Key Laboratory of Vegetation Ecology, MOE, Northeast Normal University, Changchun, China.
Jonathan D Bohbot *Department of Entomology, The Hebrew University of Jerusalem, The Robert H. Smith Faculty of Agriculture, Food and Environment, Rehovot, Israel.
Yongjuan ChiApiculture Science Institute of Jilin Province, Jilin, China.
Shiwen DuanKey Laboratory of Vegetation Ecology, MOE, Northeast Normal University, Changchun, China.
Xiaomei MaKey Laboratory of Vegetation Ecology, MOE, Northeast Normal University, Changchun, China.
Bingzhong RenKey Laboratory of Vegetation Ecology, MOE, Northeast Normal University, Changchun, China. bzren@nenu.edu.cn.
Yinliang WangKey Laboratory of Vegetation Ecology, MOE, Northeast Normal University, Changchun, China. wangyl392@nenu.edu.cn.ORCID 0009-0004-5161-3613
Northeast Normal University · CNApiculture Science Institute of Jinlin province · CNHebrew University of Jerusalem · IL

Funding

Israel Science Foundation (ISF) No. 719/21
6 · The paper itself

Abstract

In Asian honeybees, virgin queens typically only mate during a single nuptial flight before founding a colony. This behavior is controlled by the queen-released mandibular pheromone (QMP). 9-oxo-(E)-2-decenoic acid (9-ODA), a key QMP component, acts as sex pheromone and attracts drones. However, how the queens prevent additional mating remains elusive. Here, we show that the secondary QMP component methyl p-hydroxybenzoate (HOB) released by mated queens inhibits male attraction to 9-ODA. Results from electrophysiology and in situ hybridization assay indicated that HOB alone significantly reduces the spontaneous spike activity of 9-ODA-sensitive neurons, and AcerOr11 is specifically expressed in sensilla placodea from the drone's antennae, which are the sensilla that narrowly respond to both 9-ODA and HOB. Deorphanization of AcerOr11 in Xenopus oocyte system showed 9-ODA induces robust inward (regular) currents, while HOB induces inverse currents in a dose-dependent manner. This suggests that HOB potentially acts as an inverse agonist against AcerOr11.

Indexed as

Fatty Acids, MonounsaturatedSex AttractantsAnimalsBeesFemaleInsect ProteinsMaleOocytesReceptors, PheromoneSexual Behavior, Animal9-keto-2-decenoic acidFatty Acids, MonounsaturatedInsect ProteinsReceptors, PheromoneSex Attractants

Identifiers

PMID38664580
PMCPMC11045764
OpenAlexW4395447473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.