Evidence map›Paper›PMID 38664470›Full record

SynthesisSpinal cord series and cases2024

Contrast enhanced ultrasound for traumatic spinal cord injury: an overview of current and future applications.

Brian Fabian Saway, James Courtney, Jessica Barley, Bruce Frankel, Christoph Hofstetter, Stephen Kalhorn

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Spinal cord series and cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Brian Fabian Saway *Medical University of South Carolina, Department of Neurosurgery, Charleston, SC, 29425, USA. saway@musc.edu.ORCID 0000-0002-7101-0981
James Courtney *Florida State University College of Medicine, Tallahassee, FL, 32303, USA.
Jessica BarleyMedical University of South Carolina, Department of Neurosurgery, Charleston, SC, 29425, USA.
Bruce FrankelSouthern Illinois University School of Medicine, Department of Neurosurgery, Springfield, IL, 62702, USA.
Christoph HofstetterUniversity of Washington, Department of Neurosurgery, Seattle, WA, 98195, USA.
Stephen KalhornMedical University of South Carolina, Department of Neurosurgery, Charleston, SC, 29425, USA.
Medical University of South Carolina · USFlorida State University · USSouthern Illinois University School of Medicine · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic review.

objectiveContrast-enhanced ultrasound (CEUS) is an imaging modality that has only recently seen neurosurgical application. CEUS uses inert microbubbles to intraoperatively visualize vasculature and perfusion of the brain and spinal cord in real time. Observation and augmentation of spinal cord perfusion is vital component of the management of traumatic spinal cord injury, yet there are limited imaging modalities to evaluate spinal cord perfusion. CEUS provides an intraoperative imaging tool to evaluate spinal cord perfusion in real time. The objective of this review is to evaluate the current literature on the various applications and benefits of CEUS in traumatic spinal cord injury.

settingSouth Carolina, USA.

methodsThis review was written according to the PRISMA 2020 guidelines.

results143 articles were found in our literature search, with 46 of them being unique. After excluding articles for relevance to CEUS and spinal cord injury, we were left with 10 papers. Studies in animal models have shown CEUS to be an effective non-invasive imaging modality that can detect perfusion changes of injured spinal cords in real time.

conclusionThis imaging modality can provide object perfusion data of the nidus of injury, surrounding penumbra and healthy neural tissue in a traumatized spinal cord. Investigation in its use in humans is ongoing and remains promising to be an effective diagnostic and prognostic tool for those suffering from spinal cord injury.

Indexed as

Contrast MediaSpinal Cord InjuriesUltrasonographyAnimalsHumansSpinal CordContrast Media

Identifiers

PMID38664470
PMCPMC11045808
OpenAlexW4395447910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.