Evidence map›Paper›PMID 38664463›Full record

ArticleScientific reports2024

A retrospective analysis of the role of age and sex in outcomes of non-surgical periodontal therapy at a single academic dental center.

Nikola Angelov, Nikolaos Soldatos, Effie Ioannidou, Tonia C Carter, Neel Shimpi, Joseph Applegate, Krishna Kumar Kookal, Karo Parsegian

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Nikola AngelovDepartment of Periodontics and Dental Hygiene, UTHealth Houston School of Dentistry, Houston, TX, USA.ORCID 0000-0002-0800-2778
Nikolaos SoldatosDivision of Periodontics, Department of Regenerative and Reconstructive Sciences, School of Dentistry, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0002-2821-7063
Effie IoannidouDepartment of Orofacial Sciences, School of Dentistry, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-1954-5900
Tonia C CarterCenter for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, WI, USA.ORCID 0000-0002-2107-7838
Neel ShimpiCenter for Dental Benefits, Coding and Quality, American Dental Association, Chicago, IL, USA.ORCID 0000-0001-7545-622X
Joseph ApplegateBiomedical Informatics Group-Analytics Research Center, UTHealth Houston School of Dentistry, Houston, TX, USA.ORCID 0000-0002-9939-5553
Krishna Kumar KookalTechnology Services and Informatics, UTHealth Houston School of Dentistry, Houston, USA.ORCID 0000-0002-8228-5796
Karo ParsegianDepartment of Periodontics and Dental Hygiene, UTHealth Houston School of Dentistry, Houston, TX, USA. karo.parsegian@cuanschutz.edu.ORCID 0000-0002-5440-6036
The University of Texas Health Science Center at Houston · USAmerican Dental Association · USHouston Health and Human Services Department · USMarshfield Clinic · USOregon Health & Science University · USUniversity of California, San Francisco · USUniversity of Colorado Anschutz Medical Campus · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study examined the role of age and sex in the outcomes of non-surgical periodontal therapy (NSPT). De-identified demographic and periodontal characteristics of patients who presented for baseline periodontal evaluation, NSPT, and periodontal re-evaluation were abstracted from electronic health records. Independent associations of age and sex with severe periodontitis defined as ≥ 5 mm clinical attachment loss (CAL) and ≥ 6 mm probing depth (PD) were determined using multinomial logistic regression. The null hypothesis was rejected at α < 0.05. A total of 2866 eligible subjects were included in the analysis. Significantly lower odds of CAL ≤ 4 mm than CAL ≥ 5 mm (reference) were observed in adults aged 35-64 (odds ratio, OR, 0.19; 95% confidence interval, CI 0.13, 0.29) and ≥ 65 years (OR 0.13; 95% CI 0.07, 0.25) compared to those aged 18-34 years. Odds of PD < 4 mm versus PD ≥ 6 mm (reference) were lower in adults aged 35-64 years than those aged 18-34 years (OR 0.71; 95% CI 0.55, 0.90) and higher in females compared to males (OR 1.67; 95% CI 1.14, 2.44). These results suggest more compromised post-NSPT outcomes in older adults and males compared to the respective populations and highlight the need for personalized therapeutic strategies in these populations.

Indexed as

PeriodontitisAdolescentAdultAgedAge FactorsFemaleHumansMaleMiddle AgedRetrospective StudiesSex FactorsTreatment OutcomeYoung AdultAgingAssociationPeriodontitisSexTreatment outcome

Identifiers

PMID38664463
PMCPMC11045861
OpenAlexW4395677760

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.