Evidence map›Paper›PMID 38664424›Full record

ArticleNature communications2024

Ambient carbon dioxide concentration correlates with SARS-CoV-2 aerostability and infection risk.

Allen Haddrell, Henry Oswin, Mara Otero-Fernandez, Joshua F Robinson, Tristan Cogan, Robert Alexander, Jamie F S Mann, Darryl Hill, Adam Finn, Andrew D Davidson and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Allen HaddrellSchool of Chemistry, Cantock's Close, University of Bristol, Bristol, UK. A.Haddrell@bristol.ac.uk.ORCID http://orcid.org/0000-0003-0296-2791
Henry OswinSchool of Chemistry, Cantock's Close, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-4183-8593
Mara Otero-FernandezSchool of Chemistry, Cantock's Close, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-3549-850X
Joshua F RobinsonInstitut für Physik, Johannes Gutenberg-Universität Mainz, Mainz, Germany.ORCID http://orcid.org/0000-0002-2613-3667
Tristan CoganBristol Veterinary School, University of Bristol, Langford House, Langford, Bristol, UK.
Robert AlexanderSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-5864-9051
Jamie F S MannBristol Veterinary School, University of Bristol, Langford House, Langford, Bristol, UK.ORCID http://orcid.org/0000-0001-7037-1286
Darryl HillSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-5743-5078
Adam FinnSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0003-1756-5668
Andrew D DavidsonSchool of Cellular and Molecular Medicine, University of Bristol, Bristol, UK. Andrew.Davidson@bristol.ac.uk.ORCID http://orcid.org/0000-0002-1136-4008
Jonathan P ReidSchool of Chemistry, Cantock's Close, University of Bristol, Bristol, UK. J.P.Reid@bristol.ac.uk.ORCID http://orcid.org/0000-0001-6022-1778
University of Bristol · GBAt Bristol · GBJohannes Gutenberg University Mainz · DE

Funding

Medical Research Council MR/W005611/1RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/W00884X/1
6 · The paper itself

Abstract

An improved understanding of the underlying physicochemical properties of respiratory aerosol that influence viral infectivity may open new avenues to mitigate the transmission of respiratory diseases such as COVID-19. Previous studies have shown that an increase in the pH of respiratory aerosols following generation due to changes in the gas-particle partitioning of pH buffering bicarbonate ions and carbon dioxide is a significant factor in reducing SARS-CoV-2 infectivity. We show here that a significant increase in SARS-CoV-2 aerostability results from a moderate increase in the atmospheric carbon dioxide concentration (e.g. 800 ppm), an effect that is more marked than that observed for changes in relative humidity. We model the likelihood of COVID-19 transmission on the ambient concentration of CO

Indexed as

Carbon DioxideCOVID-19SARS-CoV-2AerosolsAtmosphereHumansHumidityHydrogen-Ion ConcentrationRespiratory Aerosols and DropletsVentilationAerosolsCarbon Dioxide

Identifiers

PMID38664424
PMCPMC11045827
OpenAlexW4395464088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.