Evidence map›Paper›PMID 38663929›Full record

ArticleBMJ open quality2024

Reduce intraoperative albumin utilisation in cardiac surgical patients: a quality improvement initiative.

André J Savadjian, Brad M Taicher, Jong Ok La, Mihai Podgoreanu, Timothy E Miller, Sharon McCartney, Karthik Raghunathan, Nirav Shah, Negmeldeen Mamoun

Open access · goldAbstract read
In one paragraph

Article in BMJ open quality, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

André J SavadjianAnesthesiology, Duke University Health System, Durham, North Carolina, USA.
Brad M TaicherAnesthesiology, Duke University Health System, Durham, North Carolina, USA.ORCID 0000-0001-9985-8637
Jong Ok LaDuke Molecular Physiology Institute, Duke University Hospital, Durham, North Carolina, USA.
Mihai PodgoreanuAnesthesiology, Duke University Health System, Durham, North Carolina, USA.
Timothy E MillerAnesthesiology, Duke University Health System, Durham, North Carolina, USA.
Sharon McCartneyAnesthesiology, Duke University Health System, Durham, North Carolina, USA.
Karthik RaghunathanAnesthesiology, Duke University Health System, Durham, North Carolina, USA.
Nirav ShahUniversity of Michigan, Ann Arbor, Michigan, USA.
Negmeldeen MamounAnesthesiology, Duke University Health System, Durham, North Carolina, USA negmeldeen.mamoun@duke.edu.ORCID 0000-0003-4022-487X
Duke University Health System · USDuke University Hospital · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlbumin continues to be used routinely by cardiac anaesthesiologists perioperatively despite lack of evidence for improved outcomes. The Multicenter Perioperative Outcomes Group (MPOG) data ranked our institution as one of the highest intraoperative albumin users during cardiac surgery. Therefore, we designed a quality improvement project (QIP) to introduce a bundle of interventions to reduce intraoperative albumin use in cardiac surgical patients.

methodsOur institutional MPOG data were used to analyse the FLUID-01-C measure that provides the number of adult cardiac surgery cases where albumin was administered intraoperatively by anaesthesiologists from 1 July 2019 to 30 June 2022. The QIP involved introduction of the following interventions: (1) education about appropriate albumin use and indications (January 2021), (2) email communications reinforced with OR teaching (March 2021), (3) removal of albumin from the standard pharmacy intraoperative medication trays (April 2021), (4) grand rounds presentation discussing the QIP and highlighting the interventions (May 2021) and (5) quarterly provider feedback (starting July 2021). Multivariable segmented regression models were used to assess the changes from preintervention to postintervention time period in albumin utilisation, and its total monthly cost.

resultsAmong the 5767 cardiac surgery cases that met inclusion criteria over the 3-year study period, 16% of patients received albumin intraoperatively. The total number of cases that passed the metric (albumin administration was avoided), gradually increased as our interventions went into effect. Intraoperative albumin utilisation (beta=-101.1, 95% CI -145 to -56.7) and total monthly cost of albumin (beta=-7678, 95% CI -10712 to -4640) demonstrated significant decrease after starting the interventions.

conclusionsAt a single academic cardiac surgery programme, implementation of a bundle of simple and low-cost interventions as part of a coordinated QIP were effective in significantly decreasing intraoperative use of albumin, which translated into considerable costs savings.

Indexed as

AlbuminsCardiac Surgical ProceduresQuality ImprovementAgedFemaleHumansIntraoperative CareMaleMiddle AgedAlbuminsAnaesthesiaPerformance measuresQuality improvementRegistries

Identifiers

PMID38663929
PMCPMC11043756
OpenAlexW4395478168

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.