Evidence map›Paper›PMID 38662908›Full record

ArticleThe Journal of organic chemistry2024

Anion Binding to Ammonium and Guanidinium Hosts: Implications for the Reverse Hofmeister Effects Induced by Lysine and Arginine Residues.

Jacobs H Jordan, Corinne L D Gibb, Thien Tran, Wei Yao, Austin Rose, Joel T Mague, Michael W Easson, Bruce C Gibb

Open access · hybridAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jacobs H JordanThe Southern Regional Research Center, Agricultural Research Service, US Department of Agriculture, 1100 Allen Toussaint Blvd., New Orleans, Louisiana 70124, United States.ORCID 0000-0002-0238-3864
Corinne L D GibbDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.
Thien TranDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.ORCID 0009-0001-9359-5829
Wei YaoDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.ORCID 0000-0002-4229-0486
Austin RoseDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.
Joel T MagueDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.
Michael W EassonThe Southern Regional Research Center, Agricultural Research Service, US Department of Agriculture, 1100 Allen Toussaint Blvd., New Orleans, Louisiana 70124, United States.ORCID 0000-0002-2268-1922
Bruce C GibbDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118, United States.ORCID 0000-0002-4478-4084
Tulane University · USAgricultural Research Service · US

Funding

Ion-Ion Interactions and the Reverse Hofmeister EffectR01GM125690 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI GIBB, BRUCE C · 2018 to 2021
$1.7M
NIGMS NIH HHS R01 GM125690
6 · The paper itself

Abstract

Anions have a profound effect on the properties of soluble proteins. Such Hofmeister effects have implications in biologics stability, protein aggregation, amyloidogenesis, and crystallization. However, the interplay between the important noncovalent interactions (NCIs) responsible for Hofmeister effects is poorly understood. To contribute to improving this state of affairs, we report on the NCIs between anions and ammonium and guanidinium hosts

Indexed as

Ammonium CompoundsAnionsArginineGuanidineLysineMolecular Dynamics SimulationAmmonium CompoundsAnionsArginineGuanidineLysine

Identifiers

PMID38662908
PMCPMC11110012
OpenAlexW4395446591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.