Evidence map›Paper›PMID 38662725›Full record

ArticlePloS one2024

Water intake and obesity: By amount, timing, and perceived temperature of drinking water.

Jaewon Khil, Qiao-Yi Chen, Dong Hoon Lee, Kyung-Won Hong, NaNa Keum

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jaewon KhilDepartment of Food Science and Biotechnology, Dongguk University, Goyang, South Korea.
Qiao-Yi ChenDepartment of Food Science and Biotechnology, Dongguk University, Goyang, South Korea.
Dong Hoon LeeDepartment of Sport Industry Studies, Yonsei University, Seoul, South Korea.
Kyung-Won HongTheragen Health Co. Ltd., Seongnam, South Korea.
NaNa KeumDepartment of Food Science and Biotechnology, Dongguk University, Goyang, South Korea.ORCID 0000-0003-4671-0211
Dongguk University · KRHarvard University · USTheragen · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Water intake has been suggested to be associated with weight control, but evidence for optimal water intake in terms of amount, timing, and temperature is sparse. Additionally, genetic predisposition to obesity, which affects satiety and energy expenditure, might interact with water intake in regulating individual adiposity risk. We conducted a cross-sectional study recruiting 172 Korean adults. Information on water intake and lifestyle factors was collected through self-reported questionnaires, and height, weight, and waist circumference (WC) were measured by researchers. The oral buccal swab was performed for genotyping of FTO rs9939609, MC4R rs17782313, BDNF rs6265 and genetic risk of obesity was calculated. Linear regression was performed to estimate mean difference in body mass index (BMI) and WC by water intake and its 95% confidence interval (95% CI). As a sensitivity analysis, logistic regression was performed to estimate odds ratio (OR) of obesity/overweight (BMI of ≥23kg/m2; WC of ≥90cm for men and of ≥80cm for women) and its 95% CI. Drinking >1L/day was significantly associated with higher BMI (mean difference: 0.90, 95% CI 0.09, 1.72) and WC (mean difference: 3.01, 95% CI 0.62, 5.41) compared with drinking ≤1L/day. Independent of total water intake, drinking before bedtime was significantly associated with lower BMI (mean difference: -0.98, 95% CI -1.91, -0.05). The results remained consistent when continuous BMI and WC were analyzed as categorical outcomes. By perceived temperature, drinking >1L/day of cold water was associated with higher BMI and WC compared with drinking ≤1L/day of water at room-temperature. By genetic predisposition to obesity, a positive association between water intake and WC was confined to participants with low genetic risk of obesity (P interaction = 0.04). In conclusion, amount, timing, and perceived temperature of water intake may be associated with adiposity risk and the associations might vary according to genetic predisposition to obesity.

Indexed as

Body Mass IndexDrinkingDrinking WaterObesityTemperatureAdultAlpha-Ketoglutarate-Dependent Dioxygenase FTOCross-Sectional StudiesFemaleHumansMaleMiddle AgedReceptor, Melanocortin, Type 4Waist CircumferenceAlpha-Ketoglutarate-Dependent Dioxygenase FTODrinking WaterFTO protein, humanMC4R protein, humanReceptor, Melanocortin, Type 4

Identifiers

PMID38662725
PMCPMC11045127
OpenAlexW4395448106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.