ArticleProceedings of the National Academy of Sciences of the United States of America2024
The potential importance of the built-environment microbiome and its impact on human health.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Gut Prevotella stercorea associates with protection against infection in rural African children.Nature communications · 2025Trial
- Article
- Microbial transmission and ecology of human and environmental microbial communities in childcare centers.Research square · 2026Article
- Urbanization-Associated Microbial Diversity Loss and Its Impact on Elderly Health: Integrating Environmental and Host Microbiome Dynamics.Environmental microbiology · 2026Article
- Effectiveness of Hydrogen Peroxide Nebulization Combined with Manual Cleaning in Reducing Surface-Associated Microorganisms in an Indoor Fitness Environment.Microorganisms · 2026Article
- Bioprospecting Indoor Bacteria Producing Bioactive Metabolites.Environmental microbiology reports · 2026Article
- Gnotobiology: from 19th-century global foundations to 21st-century omics - six decades of Czech contribution to microbiome research.Folia microbiologica · 2026Review
- Rethinking One Health: Microbial Foundations for Ecological Governance.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Comparative Metagenomic Studies Reveal Different Evolutionary Directions of Synthetic Indoor Microbial Communities Under Different Nutritional Conditions.International journal of molecular sciences · 2026Article
- Biofilm Formation and Plastic Degradation in Bacteria from Different Environments: Evidence for Phenotypic Acclimation and Metabolic Exaptation.Microorganisms · 2026Article
- Article
- Microbiome dynamics in the congregate environment of U.S. Army Infantry training.Microbiology spectrum · 2026Article
- A mathematical framework to correct for compositionality in microbiome data sets.Applied and environmental microbiology · 2026Article
- Life as a Categorical Information-Handling System: An Evolutionary Information-Theoretic Model of the Holobiont.Biology · 2026Review
- Exploring and defining concepts of microbiome stewardship for the indoor built environment.Sustainable microbiology · 2026Article
- The archibiome: extending engineered living materials to multiscale built environments.Frontiers in systems biology · 2026Article
- Genome-resolved surveillance and predictive ecological risk modeling of urban microbiomes.Microbiome · 2025Article
- Applying evolutionary theory to understand host-microbiome evolution.Nature ecology & evolution · 2025Review
- Human microbiome acquisition and transmission.Nature reviews. Microbiology · 2025Review
- "Dusting Off the Cobwebs": Rethinking How We Use New Antibiotics.Antibiotics (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors.
Funding
Abstract
There is increasing evidence that interactions between microbes and their hosts not only play a role in determining health and disease but also in emotions, thought, and behavior. Built environments greatly influence microbiome exposures because of their built-in highly specific microbiomes coproduced with myriad metaorganisms including humans, pets, plants, rodents, and insects. Seemingly static built structures host complex ecologies of microorganisms that are only starting to be mapped. These microbial ecologies of built environments are directly and interdependently affected by social, spatial, and technological norms. Advances in technology have made these organisms visible and forced the scientific community and architects to rethink gene-environment and microbe interactions respectively. Thus, built environment design must consider the microbiome, and research involving host-microbiome interaction must consider the built-environment. This paradigm shift becomes increasingly important as evidence grows that contemporary built environments are steadily reducing the microbial diversity essential for human health, well-being, and resilience while accelerating the symptoms of human chronic diseases including environmental allergies, and other more life-altering diseases. New models of design are required to balance maximizing exposure to microbial diversity while minimizing exposure to human-associated diseases. Sustained trans-disciplinary research across time (evolutionary, historical, and generational) and space (cultural and geographical) is needed to develop experimental design protocols that address multigenerational multispecies health and health equity in built environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.