Evidence map›Paper›PMID 38662305›Full record

Observational studyInternational ophthalmology2024

Outcomes of iStent inject combined with cataract surgery in Asian eyes: Australian data from the Fight Glaucoma Blindness international registry.

Brandon Huynh, Getiye Kibret, David Wechsler, Anne Lee, Ridia Lim, Colin Clement, Mitchell Lawlor

Erratum issuedOpen access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Brandon HuynhDepartment of Ophthalmology, Sydney Eye Hospital, 8 Macquarie St, Sydney, NSW, Australia. b.huynh@live.com.
Getiye KibretMacquarie University, Sydney, Australia.
David WechslerFaculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Anne LeeDepartment of Ophthalmology, Sydney Eye Hospital, 8 Macquarie St, Sydney, NSW, Australia.
Ridia LimDepartment of Ophthalmology, Sydney Eye Hospital, 8 Macquarie St, Sydney, NSW, Australia.
Colin ClementDepartment of Ophthalmology, Sydney Eye Hospital, 8 Macquarie St, Sydney, NSW, Australia.
Mitchell LawlorDepartment of Ophthalmology, Sydney Eye Hospital, 8 Macquarie St, Sydney, NSW, Australia.
The University of Sydney · AUSydney Hospital · AUUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyse real-world outcomes in Asian eyes of iStent inject, a second-generation trabecular micro-bypass stent, combined with phacoemulsification.

methodsThis is a multi-centre, observational study of glaucomatous Asian eyes that have undergone iStent inject implantation combined with cataract surgery. Patient data were extracted from the Fight Glaucoma Blindness! Registry. Outcome measures included those of IOP reduction, glaucoma medication reduction, and adverse events including the need for secondary surgery.

results123 eyes of 86 patients with a mean age of 68.4 ± 9.3 years underwent iStent inject implantation with phacoemulsification. At baseline, the mean ± SD preoperative intraocular pressure (IOP) was 16.0 ± 4.4 mmHg, and the mean preoperative number of topical glaucoma medications was 1.9 ± 1.4. At 12 months 30.8% of eyes demonstrated a reduction in IOP greater than 20%, the mean IOP reduction was 12.5% with an additional reduction of 0.7 glaucoma medications. 40% of eyes were using no medications at 12 months compared to 16.3% preoperatively. 8.2% of eyes required a subsequent procedure within the 12-month follow-up window.

conclusioniStent inject implantation combined with phacoemulsification in Asian eyes showed a reduction of IOP and glaucoma medication use in a real-world clinical setting. The safety profile of the device is good with minimal adverse outcomes, however, a subset of patients required secondary procedures within the 12 month follow up.

Indexed as

Intraocular PressureRegistriesAgedAged, 80 and overAsian PeopleAustraliaCataractFemaleFollow-Up StudiesGlaucomaGlaucoma Drainage ImplantsHumansMaleMiddle AgedPhacoemulsificationRetrospective StudiesGlaucomaIntraocular pressureiStent injectMinimally invasive glaucoma surgery

Identifiers

PMID38662305
PMCPMC11358208
OpenAlexW4395465041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.