Evidence map›Paper›PMID 38662303›Full record

ArticleJournal of natural medicines2024

Two new sesterterpenoids from Atractylodes japonica Koidz. ex Kitam.

Yuan-Yuan Zhou, Zhao Sun, Yan Liu, Zhen-Xing Fang, Hui-Rui Gao, Ning-Yu Liu, Xiao-Juan Zhang, Bing-You Yang, Hai-Xue Kuang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan-Yuan ZhouKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China.
Zhao SunKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China.
Yan LiuKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China.
Zhen-Xing FangInstitute of Nature and Ecology, Heilongjiang Academy of Sciences, 150040, Harbin, People's Republic of China.
Hui-Rui GaoKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China.
Ning-Yu LiuKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China.
Xiao-Juan ZhangAcademic research department, Heilongjiang University of Traditional Chinese Medicine, 150040, Harbin, People's Republic of China.
Bing-You YangKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China. ybywater@163.com.
Hai-Xue KuangKey Laboratory of Basic and Application Research of Beiyao, Ministry of Education, (Heilongjiang University of Chinese Medicine), 150040, Harbin, People's Republic of China. hxkuang@yahoo.com.

Funding

Heilongjiang Touyan Innovation Team Program 2019-5-39Natural Science Foundation of Heilongjiang Province LH2019H048Postdoctoral Research Foundation of China 2013M530164
6 · The paper itself

Abstract

Two new sesterterpenoids, atractylodes japonica terpenoid acid I (1) and atractylodes japonica terpenoid aldehyde I (2), were isolated from the rhizomes of Atractylodes japonica Koidz. ex Kitam together with ten known compounds (3-12). Their structures were elucidated on the basis of comprehensive spectroscopic analysis (1D/2D NMR, HRESIMS and IR). In addition, all of these isolated compounds were evaluated for their cytotoxic activities against human gastric cancer cell MGC-803 and human hepatocellular cancer cell HepG-2. Most of them exhibited moderate to weak inhibitory effects with IC

Indexed as

AtractylodesRhizomeSesterterpenesAntineoplastic Agents, PhytogenicCell Line, TumorHep G2 CellsHumansMagnetic Resonance SpectroscopyMolecular StructurePlant ExtractsAntineoplastic Agents, PhytogenicPlant ExtractsSesterterpenesAtractylodes japonica KoidzCytotoxic activitiesEx KitamSesterterpenoidsStructure elucidation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.