Evidence map›Paper›PMID 38662157›Full record

SynthesisDigestive diseases and sciences2024

Effects of Exercise Training on Muscle Mass and Physical Function in Patients with Hepatocellular Carcinoma After Diagnosis: A Systematic Review.

Camille Marcantei, Alexis Couret, James King, Simon Mazeaud, Abergel Armand, Gaël Ennequin

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Camille MarcanteiLaboratory of the Metabolic Adaptations to Exercise Training Under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, CRNH Auvergne, Campus Universitaire Des Cézeaux, 3 Rue de La Chébarde, 63178, Clermont-Ferrand, AUBIERE Cedex, France. Camille.MARCANTEI@etu.UCA.fr.ORCID http://orcid.org/0009-0002-0470-2408
Alexis CouretLaboratory of the Metabolic Adaptations to Exercise Training Under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, CRNH Auvergne, Campus Universitaire Des Cézeaux, 3 Rue de La Chébarde, 63178, Clermont-Ferrand, AUBIERE Cedex, France.
James KingNational Centre for Sport and Exercise Training Medicine, School of Sport, Exercise Training and Health Sciences, Loughborough University, Loughborough, UK.
Simon MazeaudLaboratory of the Metabolic Adaptations to Exercise Training Under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, CRNH Auvergne, Campus Universitaire Des Cézeaux, 3 Rue de La Chébarde, 63178, Clermont-Ferrand, AUBIERE Cedex, France.
Abergel ArmandDepartment of Digestive and Hepatobiliary Medecine, CHU, Clermont-Ferrand, France.
Gaël EnnequinLaboratory of the Metabolic Adaptations to Exercise Training Under Physiological and Pathological Conditions (AME2P), Clermont Auvergne University, CRNH Auvergne, Campus Universitaire Des Cézeaux, 3 Rue de La Chébarde, 63178, Clermont-Ferrand, AUBIERE Cedex, France.
Université Clermont Auvergne · FRCentre National de la Recherche Scientifique · FRLoughborough University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsDecreased muscle mass and physical function are common complications in hepatocellular carcinoma (HCC) patients who are associated with increased morbidity and mortality. Thus, there have been targeted efforts to prevent and/or improve both by enrolling these patients in exercise training programs. We performed a systematic review to evaluate the effects of exercise training on muscle mass and physical function in people with HCC after diagnosis.

methodsA systematic literature search was conducted using the Medline, Base, PubMed, Cochrane and Scopus, and trial registries, through April 2023 for studies that assessed the effects of an exercise training program in adults with HCC. The primary outcomes were muscle mass and physical function. To assess the risk of bias, we used the Quality Assessment Tool for Quantitative Studies from the Effective Public Health Practice Project.

resultsEight studies met inclusion criteria, comprising a total of 809 participants. Interventions included aerobic exercise training, resistance exercise training, balance and flexibility training, or home-based exercise training. Four studies showed statistically significant improvements in at least one muscular outcome. Three studies showed a maintenance of muscular outcomes, and one study showed a decrease in muscle mass. Four articles showed statistically improvements in at least one physical fitness variable, and two showed a maintenance of physical function variable.

conclusionTogether, the results suggest that patients may benefit from physical exercise training after treatment to improve muscle mass and physical function.

Indexed as

Carcinoma, HepatocellularExercise TherapyLiver NeoplasmsExerciseHumansMuscle, SkeletalMuscle StrengthSarcopeniaExerciseHepatocellular carcinomaHospitalizationPhysical functionSarcopenia

Identifiers

PMID38662157
OpenAlexW4395465492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.