Evidence map›Paper›PMID 38662092›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2025

Altered patterns of dynamic functional connectivity of brain networks in deficit and non-deficit schizophrenia.

Biying Ye, Yiqiao Wu, Mingjun Cao, Chanhuan Xu, Chao Zhou, Xiangrong Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Biying Ye *Department of Fourth Clinical Medical College, Nanjing Medical University, Nanjing, China.
Yiqiao Wu *Department of Fourth Clinical Medical College, Nanjing Medical University, Nanjing, China.
Mingjun Cao *Department of Fourth Clinical Medical College, Nanjing Medical University, Nanjing, China.
Chanhuan XuDepartment of Fourth Clinical Medical College, Nanjing Medical University, Nanjing, China.
Chao ZhouDepartment of Geriatric Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, No.264 Guangzhou Road, Nanjing, 210029, Jiangsu, China. zc35201@163.com.ORCID http://orcid.org/0000-0001-6114-0048
Xiangrong ZhangDepartment of Geriatric Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, No.264 Guangzhou Road, Nanjing, 210029, Jiangsu, China. drxrz@hotmail.com.

Funding

National Natural Science Foundation of China 81971255National Natural Science Foundation of China 82101572
6 · The paper itself

Abstract

This study aims to investigate the altered patterns of dynamic functional network connectivity (dFNC) between deficit schizophrenia (DS) and non-deficit schizophrenia (NDS), and further explore the associations with cognitive impairments. 70 DS, 91 NDS, and 120 matched healthy controls (HCs) were enrolled. The independent component analysis was used to segment the whole brain. The fMRI brain atlas was used to identify functional networks, and the dynamic functional connectivity (FC) of each network was detected. Correlation analysis was used to explore the associations between altered dFNC and cognitive functions. Four dynamic states were identified. Compared to NDS, DS showed increased FC between sensorimotor network and default mode network in state 1 and decreased FC within auditory network in state 4. Additionally, DS had a longer mean dwell time of state 2 and a shorter one in state 3 compared to NDS. Correlation analysis showed that fraction time and mean dwell time of states were correlated with cognitive impairments in DS. This study demonstrates the distinctive altered patterns of dFNC between DS and NDS patients. The associations with impaired cognition provide specific neuroimaging evidence for the pathogenesis of DS.

Indexed as

BrainCognitive DysfunctionConnectomeDefault Mode NetworkNerve NetSchizophreniaAdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedYoung AdultDeficit schizophreniaDynamic functional network connectivityGroup ICANegative symptomsNeurocognition

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.