Evidence map›Paper›PMID 38661532›Full record

ArticleeLife2024

Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice.

Ang Li, Jianxun Yi, Xuejun Li, Li Dong, Lyle W Ostrow, Jianjie Ma, Jingsong Zhou

Open access · goldAbstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Ang LiDepartment of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, United States.ORCID https://orcid.org/0000-0002-8784-4702
Jianxun YiDepartment of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, United States.
Xuejun LiDepartment of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, United States.
Li DongDepartment of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, United States.
Lyle W OstrowDepartment of Neurology, Lewis Katz School of Medicine at Temple University, Philadelphia, United States.ORCID https://orcid.org/0000-0001-7158-5243
Jianjie MaDepartment of Surgery, Division of Surgical Sciences, University of Virginia, Charlottesville, United States.
Jingsong ZhouDepartment of Kinesiology, College of Nursing and Health Innovation, The University of Texas at Arlington, Arlington, United States.ORCID https://orcid.org/0000-0002-5684-7177
The University of Texas at Arlington · US

Funding

MG53 function in muscle agingR01AG071676 · NIA · UNIVERSITY OF VIRGINIA · PI Jianjie Ma, Ki Ho Park · 2022 to 2026
$3.1M
Preserving Mitochondrial Function for Alleviating ALS ProgressionR01NS105621 · NINDS · UNIVERSITY OF TEXAS ARLINGTON · PI BROTTO, MARCO, ZHOU, JINGSONG · 2019 to 2023
$2.9M
Multifaceted role of MG53 in alleviating neuromuscular function decline in ALSR01NS129219 · NINDS · UNIVERSITY OF TEXAS ARLINGTON · PI Jianjie Ma, Lyle Wilfred Ostrow · 2023 to 2026
$2.5M
NIA NIH HHS R01 AG071676NIH HHS R01AG071676NIH HHS R01NS105621NIH HHS R01NS129219NINDS NIH HHS R01 NS105621NINDS NIH HHS R01 NS129219
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disorder characterized by progressive weakness of almost all skeletal muscles, whereas extraocular muscles (EOMs) are comparatively spared. While hindlimb and diaphragm muscles of end-stage SOD1G93A (G93A) mice (a familial ALS mouse model) exhibit severe denervation and depletion of Pax7

Indexed as

Amyotrophic Lateral SclerosisDisease Models, AnimalNeuromuscular JunctionSatellite Cells, Skeletal MuscleTranscriptomeAnimalsMiceMice, TransgenicOculomotor Musclesamyotrophic lateral sclerosiscell biologychemokinemouseneuromuscular junctionsatellite cell

Identifiers

PMID38661532
PMCPMC11045223
OpenAlexW4388304127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.