Evidence map›Paper›PMID 38661249›Full record

ArticleTransfusion2024

Changes in transfusion-transmissible infection prevalence and demographics among US blood donors during the COVID-19 pandemic.

Galen Conti, Edward P Notari, Roger Y Dodd, Debra Kessler, Brian Custer, Roberta Bruhn, Rita Reik, Hong Yang, Barbee I Whitaker, Susan L Stramer and 1 more

Open access · greenAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Galen ContiAmerican Red Cross, Rockville, Maryland, USA.ORCID 0000-0003-2507-9141
Edward P NotariAmerican Red Cross, Rockville, Maryland, USA.
Roger Y DoddAmerican Red Cross, Rockville, Maryland, USA.
Debra KesslerNew York Blood Center Enterprises, New York, New York, USA.
Brian CusterVitalant Research Institute, San Francisco, California, USA.ORCID 0000-0001-6251-366X
Roberta BruhnVitalant Research Institute, San Francisco, California, USA.ORCID 0000-0002-5898-8168
Rita ReikOneBlood, St. Petersburg, Florida, USA.
Hong YangUS Food and Drug Administration, Silver Spring, Maryland, USA.
Barbee I WhitakerUS Food and Drug Administration, Silver Spring, Maryland, USA.ORCID 0000-0002-6311-6268
Susan L StramerInfectious Disease Consultant, North Potomac, Maryland, USA.ORCID 0000-0002-5865-6366
U.S. Transfusion‐Transmissible Infections Monitoring System (TTIMS)
American Red Cross · USUnited States Food and Drug Administration · USNew York Blood Center · USOneBlood · USPacific Research Institute · USUniversity of California, San Francisco · USUniversity of the Potomac · US

Funding

NIH HHSOffice of the Assistant Secretary for HealthU.S. Food and Drug Administration
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic impacted the US blood supply. We compared blood donor demography and infectious disease prevalence before and during the pandemic using a large multicenter database.

methodsData were categorized as "Before COVID-19" (March 2018-February 2020) or "During COVID-19" (March 2020-February 2022). Donor demographics, donation frequency, and infectious marker prevalence of HIV, HBV, and HCV were compared for the two time periods. The odds of a donor testing positive for these infections among the two time periods were calculated using multivariable logistic regression.

resultsOur study assessed a total of 26,672,213 donations including 13,430,380 before and 13,241,833 during COVID-19. There were significantly more donations from donors who were female, aged 40 and older, white, and repeat, during COVID-19. Donation frequency comparison quantified the increase in donations from donors who were white, female, older, and repeat during the pandemic. The prevalence of HIV and HCV decreased significantly during COVID-19 compared to before, but not for HBV. For HIV, the adjusted odds of infection during the pandemic did not differ but for HBV, the odds were significantly more likely during the pandemic and were significantly lower for HCV. DISCUSSION: Demographics and infectious disease marker prevalence changed during the COVID-19 pandemic in the United States. Prevalence of each infection in the donor population will continue to be monitored to determine if changes were specific to the pandemic period.

Indexed as

Blood DonorsCOVID-19SARS-CoV-2AdolescentAdultAgedDemographyFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleMiddle AgedPandemicsPrevalenceblood donorsCOVID‐19demographyHBVHCVHIV

Identifiers

PMID38661249
PMCPMC11144079
OpenAlexW4395464455

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.