Evidence map›Paper›PMID 38661126›Full record

ReviewCritical reviews in biochemistry and molecular biology

Elucidating the chain of command: our current understanding of critical target genes for p53-mediated tumor suppression.

Alexandra Indeglia, Maureen E Murphy

Open access · hybridAbstract readReview
In one paragraph

Review in Critical reviews in biochemistry and molecular biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Prunin: An Emerging Anticancer Flavonoid.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexandra IndegliaMolecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA, USA.
Maureen E MurphyMolecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA, USA.
The Wistar Institute · US

Funding

Functional Analysis of p53 Polymorphic Variants - Diversity SupplementR01CA102184 · NCI · WISTAR INSTITUTE · PI Maureen E. Murphy · 2005 to 2026
$7.4M
The impact of coding region variants on mutant p53 biologyR01CA238611 · NCI · WISTAR INSTITUTE · PI MURPHY, MAUREEN E. · 2020 to 2024
$2.2M
The genetics of tumor suppression by p53 - Diversity SupplementR01CA279585 · NCI · WISTAR INSTITUTE · PI Maureen E. Murphy · 2023 to 2026
$1.7M
Role of PADI4 as a key epigenetic regulator of the p53 pathway and tumor suppressionF31CA277953 · NCI · UNIVERSITY OF PENNSYLVANIA · PI INDEGLIA, ALEXANDRA · 2023 to 2024
$55k
NCI NIH HHS F31 CA277953NCI NIH HHS R01 CA102184NCI NIH HHS R01 CA238611NCI NIH HHS R01 CA279585
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NeoplasmsTumor Suppressor Protein p53AnimalsGene Expression Regulation, NeoplasticGenes, Tumor SuppressorHumansTumor Suppressor Protein p53apoptosiscancerp53transcriptiontumor suppressor

Identifiers

PMID38661126
PMCPMC11209770
OpenAlexW4395452595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.