Evidence map›Paper›PMID 38661036›Full record

ArticleCurrent pharmaceutical design2024

Green Synthesis of Silver Nanoparticles using

Mahnaz Mohtashami, Alieh Rezagholizade-Shirvan, Zahra Hojati Bonab, Mohammad Reza Amiryousefi, Majid Darroudi, Mobina Sadat Ahmadi Solimani, Sajad Yaghoobi, Samaneh Dolatabadi, Ahmad Ghasemi, Amir Abbas Momtazi-Borojeni

Abstract read
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Article in Current pharmaceutical design, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mahnaz MohtashamiDepartment of Microbiology, School of Basic Science, Islamic Azad University, Neyshabur Branch, Neyshabur, Iran.
Alieh Rezagholizade-ShirvanDepartment of Food Science and Technology, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Zahra Hojati BonabDepartment of Microbiology, School of Basic Science, Islamic Azad University, Bonab Branch, Bonab, Iran.
Mohammad Reza AmiryousefiDepartment of Food Science and Technology, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Majid DarroudiNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mobina Sadat Ahmadi SolimaniDepartment of Microbiology, School of Basic Science, Islamic Azad University, Neyshabur Branch, Neyshabur, Iran.
Sajad YaghoobiDepartment of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Samaneh DolatabadiDepartment of Microbiology, School of Basic Science, Islamic Azad University, Neyshabur Branch, Neyshabur, Iran.
Ahmad GhasemiDepartment of Biochemistry, Nutrition and Food Sciences, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
Amir Abbas Momtazi-BorojeniHealthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran.
University of Neyshabur · IRIslamic Azad University, Tehran · IRIslamic Azad University, Bonab Branch · IR

Funding

Neyshabur University of Medical Sciences 140001289, IR.NUMS.REC.1401.008
6 · The paper itself

Abstract

aimThe study aimed to determine

backgroundAgNPs are considered antimicrobial agents. However, the cytotoxicity of chemically synthesized AgNPs (cAgNPs) has raised challenges that limit their use.

objectiveThe purpose of the study was to examine the antimicrobial and cytotoxicity effects of AgNPs synthesized using

methodsNanoparticles were characterized using TEM, DLS, XRD, and FTIR. Resistant strains of

resultsPhysicochemical characterizations confirmed Ch/ALG-gAgNPs to be spherical and uniformly dispersed, and their size ranged from 50 to 500 nm. Ch/ALG-gAgNPs inhibited the growth of microbial strains in a dose-dependent manner. The antibacterial effect of Ch/ALG-gAgNPs was significantly higher than cAgNPs. The Ch/ALG-gAgNPs showed little cytotoxicity against normal cells at concentrations less than 50 μg/ml. Cytotoxicity effects of Ch/ALG-gAgNP were less than cAgNPs. Flow cytometry and real-time PCR results showed a decrease in apoptosis percentage and BAX marker in the presence of Ch/ALG-gAgNPs relative to when the cell was treated with cAgNPs.

conclusionCurrent findings introduce novel gAgNPs modified with chitosan/alginate for use in medicine.

Indexed as

AlginatesAnti-Bacterial AgentsCell SurvivalChitosanCirsiumEscherichia coliGreen Chemistry TechnologyMetal NanoparticlesMicrobial Sensitivity TestsPlant ExtractsSilverStaphylococcus aureusAnimalsApoptosisCell LineDose-Response Relationship, DrugAlginatesAnti-Bacterial AgentsChitosanPlant ExtractsSilveralginateantibacterial activitycell apoptosis.chitosancytotoxicityGreen synthesis

Identifiers

PMID38661036
OpenAlexW4395453054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.