ArticleHypertension (Dallas, Tex. : 1979)2024
Sex-Related Disparities in Cardiovascular Outcomes Among Older Adults With Late-Onset Hypertension.
Article in Hypertension (Dallas, Tex. : 1979), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Timing of Orthostatic Blood Pressure Changes and Its Association With Orthostatic Symptoms and Falls at Very Old Ages: Findings From the ARIC Study.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Age- and Sex-specific Prevalence, Longitudinal Trends and Factors of Cardiovascular-Kidney-Metabolic Syndrome Stages among Chinese Adults.npj aging · 2026Article
- Older females with late-onset hypertension are at higher CKD risk than males.Clinical kidney journal · 2026Article
- Sex-Specific Blood Pressure Thresholds in Middle-Aged Adults.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Association of estimated muscle mass and its changes with all-cause mortality: a Chinese population-based cohort study.BMC geriatrics · 2026Article
- Gender differences in the relationships between weekday sleep duration, weekend catch-up sleep, and hypertension.BMC public health · 2025Article
- Endothelial Activation and Stress Index Predicts All-Cause and Cardiovascular Mortality in Hypertensive Individuals: A Nationwide Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
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Authors and funding
12 authors.
Funding
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Abstract
backgroundIt is unclear whether sex-based differences in cardiovascular outcomes exist in late-onset hypertension.
methodsThis is a population-based cohort study in Ontario, Canada of 266 273 adults, aged ≥66 years with newly diagnosed hypertension. We determined the incidence of the primary composite cardiovascular outcome (myocardial infarction, stroke, and congestive heart failure), all-cause mortality, and cardiovascular death by sex using Cox proportional hazard models adjusted for demographic factors and comorbidities.
resultsThe mean age of the total cohort was 74 years, and 135 531 (51%) were female. Over a median follow-up of 6.6 (4.7-9.0) years, females experienced a lower crude incidence rate (per 1000 person-years) than males for the primary composite cardiovascular outcome (287.3 versus 311.7), death (238.4 versus 251.4), and cardiovascular death (395.7 versus 439.6),
conclusionsFemales had a lower risk of cardiovascular outcomes compared with males within a population characterized by advanced age and new hypertension. Our results highlight that the severity of outcomes is influenced by sex in relation to the age at which hypertension is diagnosed. Further studies are required to identify sex-specific variations in the diagnosis and management of late-onset hypertension due to its high incidence in this group.
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