Evidence map›Paper›PMID 38660779›Full record

SynthesisGlobal health action2024

The role of chest X-ray in the diagnosis of neonatal respiratory distress syndrome: a systematic review concerning low-resource birth scenarios.

Gabriela Silveira Neves, Zilma Silveira Nogueira Reis, Roberta Maia de Castro Romanelli, Jannine Dos Santos Nascimento, André Dias Sanglard, James Batchelor

Abstract readSystematic Review
In one paragraph

Synthesis in Global health action, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  3. Intraoperative full-spine imaging with C-arm using a deep learning-based automatic stitching model: development and clinical validation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriela Silveira NevesPostgraduate Program in Health Sciences: Child and Adolescent Health - PPGSCA, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Brazil.ORCID 0000-0001-6765-2968
Zilma Silveira Nogueira ReisPostgraduate Program in Health Sciences: Child and Adolescent Health - PPGSCA, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Brazil.
Roberta Maia de Castro RomanelliPostgraduate Program in Health Sciences: Child and Adolescent Health - PPGSCA, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Brazil.
Jannine Dos Santos NascimentoSofia Feldman Hospital, Neonatal Intensive Care Unit, Belo Horizonte, Brazil.
André Dias SanglardPostgraduate Program in Health Sciences: Child and Adolescent Health - PPGSCA, Faculty of Medicine, Federal University of Minas Gerais, UFMG, Belo Horizonte, Brazil.
James BatchelorClinical Informatics and Healthcare Innovation, Faculty of Medicine, University of Southampton, Southampton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccess to diagnostic tools like chest radiography (CXR) is challenging in resource-limited areas. Despite reduced reliance on CXR due to the need for quick clinical decisions, its usage remains prevalent in the approach to neonatal respiratory distress syndrome (NRDS).

objectivesTo assess CXR's role in diagnosing and grading NRDS severity compared to current clinical features and laboratory standards.

methodsA review of studies with NRDS diagnostic criteria was conducted across six databases (MEDLINE, EMBASE, BVS, Scopus-Elsevier, Web of Science, Cochrane) up to 3 March 2023. Independent reviewers selected studies, with discrepancies resolved by a senior reviewer. Data were organised into descriptive tables to highlight the use of CXR and clinical indicators of NRDS.

resultsOut of 1,686 studies screened, 23 were selected, involving a total of 2,245 newborns. All selected studies used CXR to diagnose NRDS, and 21 (91%) applied it to assess disease severity. While seven reports (30%) indicated that CXR is irreplaceable by other diagnostic tools for NRDS diagnosis, 10 studies (43%) found that alternative methods surpassed CXR in several respects, such as severity assessment, monitoring progress, predicting the need for surfactant therapy, foreseeing Continuous Positive Airway Pressure failure, anticipating intubation requirements, and aiding in differential diagnosis.

conclusionCXR remains an important diagnostic tool for NRDS. Despite its continued use in scientific reports, the findings suggest that the study's outcomes may not fully reflect the current global clinical practices, especially in low-resource settings where the early NRDS approach remains a challenge for neonatal survival.

Indexed as

Radiography, ThoracicRespiratory Distress Syndrome, NewbornDeveloping CountriesHealth ResourcesHumansInfant, NewborndiagnosisInfant, newbornlungneonatal respiratory distress syndromeradiography

Identifiers

PMID38660779
PMCPMC11047214

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.