Evidence map›Paper›PMID 38660601›Full record

ArticleRoyal Society open science2024

Kappa-carrageenan and sodium alginate-based pH-responsive hydrogels for controlled release of methotrexate.

Muhammad Anees Ur Rehman Qureshi, Nasima Arshad, Atta Rasool, Naveed Kausar Janjua, Muhammad Shoaib Butt, Muhammad Naqeeb Ur Rehman Qureshi, Hammad Ismail

Abstract read
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muhammad Anees Ur Rehman QureshiDepartment of Chemistry, Allama Iqbal Open University, Islamabad, Pakistan.
Nasima ArshadDepartment of Chemistry, Allama Iqbal Open University, Islamabad, Pakistan.ORCID https://orcid.org/0000-0002-4257-9909
Atta RasoolSchool of Chemistry, University of the Punjab, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-7743-0469
Naveed Kausar JanjuaDepartment of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan.
Muhammad Shoaib ButtSchool of Chemical and Materials Engineering (SCME), National University of Science and Technology, Islamabad 44000, Pakistan.
Muhammad Naqeeb Ur Rehman QureshiFaculty of Sciences, Department of Zoology and Biology, Pir Mehr Ali Shah ARID Agriculture University, Rawalpindi, Pakistan.
Hammad IsmailDepartment of Biochemistry and Biotechnology, University of Gujrat, Gujrat, 50700 , Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite remarkable progress in medical sciences, modern man is still fighting the battle against cancer. In 2022, only in the USA, 640 000 deaths and 2 370 000 patients were reported because of cancer. Chemotherapy is the most widely used for cancer treatments. However, chemotherapeutics have severe physicochemical side effects. Therefore, we have prepared poly(amididoamine) dendrimeric carrageenan (CG), sodium alginate (SA) and poly(vinyl alcohol) (PVA) hydrogels by using solution casting methodology. The constituents of hydrogels were cross-linked by mutable quantity of 3-aminopropyl(diethoxy)methyl silane (APDMS). Hydrogels were characterized by Fourier transform infrared spectroscopy, thermal gravimetric analysis, scanning electron microscope and atomic force microscopy. Hydrogels exhibited higher swelling volumes in 5-7 pH range.

Indexed as

alginatecancercarrageenanhydrogelsmethotrexatepoly(vinyl alcohol)

Identifiers

PMID38660601
PMCPMC11040253

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.