Evidence map›Paper›PMID 38660600›Full record

ArticleRoyal Society open science2024

Active viscoelastic models for cell and tissue mechanics.

Bahareh Tajvidi Safa, Changjin Huang, Alexandre Kabla, Ruiguo Yang

Open access · goldAbstract read
In one paragraph

Article in Royal Society open science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. PIEZO1-mediated mechanosensation links aging to bladder dysfunction.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Physical models of embryonic epithelial healing.PLoS computational biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Bahareh Tajvidi SafaDepartment of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID https://orcid.org/0000-0003-1280-5319
Changjin HuangSchool of Mechanical & Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore.
Alexandre KablaDepartment of Engineering, University of Cambridge, Cambridge CB2 1PZ, UK.ORCID https://orcid.org/0000-0002-0280-3531
Ruiguo YangDepartment of Mechanical and Materials Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID https://orcid.org/0000-0002-1361-4277
University of Nebraska–Lincoln · USNanyang Technological University · SGUniversity of Cambridge · GB

Funding

Direct and Quantitative Probing of Desmosome MechanotransductionR35GM150623 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI Ruiguo Yang · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM150623
6 · The paper itself

Abstract

Living cells are out of equilibrium active materials. Cell-generated forces are transmitted across the cytoskeleton network and to the extracellular environment. These active force interactions shape cellular mechanical behaviour, trigger mechano-sensing, regulate cell adaptation to the microenvironment and can affect disease outcomes. In recent years, the mechanobiology community has witnessed the emergence of many experimental and theoretical approaches to study cells as mechanically active materials. In this review, we highlight recent advancements in incorporating active characteristics of cellular behaviour at different length scales into classic viscoelastic models by either adding an active tension-generating element or adjusting the resting length of an elastic element in the model. Summarizing the two groups of approaches, we will review the formulation and application of these models to understand cellular adaptation mechanisms in response to various types of mechanical stimuli, such as the effect of extracellular matrix properties and external loadings or deformations.

Indexed as

active modelcell mechanicscell modelingtissue mechanicsviscoelasticity

Identifiers

PMID38660600
PMCPMC11040246
OpenAlexW4395111305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.