Evidence map›Paper›PMID 38660526›Full record

ArticleRSC advances2024

Synthesis of novel phthalazine-based derivatives with potent cytotoxicity against HCT-116 cells through apoptosis and VEGFR2 inhibition.

Donia El Sayed, Samir M El Rayes, Hamdy A Soliman, Imad Eddin AlBalaa, Mansour S Alturki, Abdulaziz Hassan Al Khzem, Mohammed Abdullah Alsharif, Mohamed S Nafie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Donia El SayedChemistry Department, Faculty of Science, Suez Canal University P.O. 41522 Ismailia Egypt mohamed_nafie@science.suez.edu.eg samir_elrayes@science.suez.edu.eg.
Samir M El RayesChemistry Department, Faculty of Science, Suez Canal University P.O. 41522 Ismailia Egypt mohamed_nafie@science.suez.edu.eg samir_elrayes@science.suez.edu.eg.ORCID https://orcid.org/0000-0003-2667-3855
Hamdy A SolimanChemistry Department, Faculty of Science, Suez Canal University P.O. 41522 Ismailia Egypt mohamed_nafie@science.suez.edu.eg samir_elrayes@science.suez.edu.eg.
Imad Eddin AlBalaaScience Department, Faculty of Basic Educations, PAAET Kuwait Safat 22081 Kuwait.ORCID https://orcid.org/0000-0001-7159-1758
Mansour S AlturkiDepartment of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University P.O. Box 1982 Dammam 31441 Eastern Province Kingdom of Saudi Arabia.
Abdulaziz Hassan Al KhzemDepartment of Pharmaceutical Chemistry, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University P.O. Box 1982 Dammam 31441 Eastern Province Kingdom of Saudi Arabia.
Mohammed Abdullah AlsharifKing Fahad Armed Forces Hospital Al Kurnaysh Rd, Al Andalus Jeddah 23311 Kingdom of Saudi Arabia.
Mohamed S NafieChemistry Department, Faculty of Science, Suez Canal University P.O. 41522 Ismailia Egypt mohamed_nafie@science.suez.edu.eg samir_elrayes@science.suez.edu.eg.ORCID https://orcid.org/0000-0003-4454-6390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The parent ethyl 3-(4-benzyl-1-oxophthalazin-2(1

Identifiers

PMID38660526
PMCPMC11040327

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.