Evidence map›Paper›PMID 38660466›Full record

ArticleFrontiers in synaptic neuroscience2024

Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses.

Yucui Chen, Shangming Liu, Ariel A Jacobi, Grace Jeng, Jason D Ulrich, Ivar S Stein, Tommaso Patriarchi, Johannes W Hell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Designing Neural Dynamics: From Digital Twin Modeling to Regeneration.International journal of molecular sciences · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yucui Chen *Department of Pharmacology, University of Iowa, Iowa City, IA, United States.
Shangming Liu *Department of Pharmacology, University of California, Davis, Davis, CA, United States.
Ariel A JacobiDepartment of Pharmacology, University of California, Davis, Davis, CA, United States.
Grace JengDepartment of Pharmacology, University of California, Davis, Davis, CA, United States.
Jason D UlrichDepartment of Pharmacology, University of Iowa, Iowa City, IA, United States.
Ivar S SteinDepartment of Pharmacology, University of Iowa, Iowa City, IA, United States.
Tommaso PatriarchiDepartment of Pharmacology, University of California, Davis, Davis, CA, United States.
Johannes W HellDepartment of Pharmacology, University of Iowa, Iowa City, IA, United States.
University of California, Davis · USUniversity of Iowa · US

Funding

Role of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0M
Postsynaptic Signaling by Norepinephrine and cAMPR01NS123050 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2022 to 2026
$2.3M
Dysregulation of Cav1.2 by beta amyloid peptideRF1AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2022 to 2024
$1.7M
NIA NIH HHS RF1 AG055357NINDS NIH HHS R01 NS123050
6 · The paper itself

Abstract

Rapid, synapse-specific neurotransmission requires the precise alignment of presynaptic neurotransmitter release and postsynaptic receptors. How postsynaptic glutamate receptor accumulation is induced during maturation is not well understood. We find that in cultures of dissociated hippocampal neurons at 11 days

Indexed as

AMPA receptor (AMPAR)calciumcalmodulin (CAM)CaMKIINMDA receptor (NMDAR)synapse

Identifiers

PMID38660466
PMCPMC11039796
OpenAlexW4394684816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.