Evidence map›Paper›PMID 38660397›Full record

ArticleiScience2024

Conditional deletion of Zeb1 in Csf1r

Khoi K Do, Fuhua Wang, Xiaolei Sun, Yingnan Zhang, Wei Liang, John Y Liu, Daniel Y Jiang, Xiaoqin Lu, Wei Wang, Lijun Zhang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Role of ZEB1 in angiogenesis and therapeutic potential (Review).International journal of molecular medicine · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Khoi K DoDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Fuhua WangDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Xiaolei SunDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Yingnan ZhangDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Wei LiangDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
John Y LiuDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Daniel Y JiangDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Xiaoqin LuDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Wei WangDepartment of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Lijun ZhangDepartment of Ophthalmology, Third People's Hospital of Dalian, Dalian Medical University, Dalian 116033, China.
Douglas C DeanDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Yongqing LiuDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY 40202, USA.
University of Louisville · USDalian Medical University · CN

Funding

Summer Vision Sciences Training ProgramT35EY026509 · NEI · UNIVERSITY OF LOUISVILLE · PI BRIAN P. CERESA, Maureen A McCall · 2017 to 2026
$416k
NEI NIH HHS T35 EY026509
6 · The paper itself

Abstract

ZEB1 is an essential factor in embryonic development. In adults, it is often highly expressed in malignant tumors with low expression in normal tissues. The major biological function of ZEB1 in developing embryos and progressing cancers is to transdifferentiate cells from an epithelial to mesenchymal phenotype; but what roles ZEB1 plays in normal adult tissues are largely unknown. We previously reported that the reduction of Zeb1 in monoallelic global knockout (Zeb1

Indexed as

ImmunologyOphthalmology

Identifiers

PMID38660397
PMCPMC11039400
OpenAlexW4394601969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.