Evidence map›Paper›PMID 38660335›Full record

ArticlePlastic and reconstructive surgery. Global open2024

Modulation of Cellular Stemness for Enhanced Fat Grafting.

Amin Izadpanah, Abigail E Chaffin, David A Jansen, Eckhard U Alt, Reza Izadpanah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Amin IzadpanahFrom Applied Stem Laboratory, Heart and Vascular Institute, Department of Medicine, Tulane University Health Science Center, New Orleans, La.
Abigail E ChaffinDivision of Plastic and Reconstructive Surgery, Tulane University School of Medicine, New Orleans, La.
David A JansenDivision of Plastic and Reconstructive Surgery, Tulane University School of Medicine, New Orleans, La.
Eckhard U AltFrom Applied Stem Laboratory, Heart and Vascular Institute, Department of Medicine, Tulane University Health Science Center, New Orleans, La.
Reza IzadpanahFrom Applied Stem Laboratory, Heart and Vascular Institute, Department of Medicine, Tulane University Health Science Center, New Orleans, La.
Tulane University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low volumetric retention limits the utility of fat grafting. Although inclusion of stem cells and platelet-rich plasma have been proposed to enhance graft retention, accumulating evidence has failed to show a clear benefit. Here, we propose a strategy to pharmacologically enhance stemness of stem and progenitor cell populations in fat grafts to promote increased volume retention and tissue health. We also propose how to integrate stemness-promoting and differentiation-promoting therapies such as platelet-rich plasma, and viability promoting therapies within the common fat grafting workflow to achieve optimal fat grafting results.

Identifiers

PMID38660335
PMCPMC11042767
OpenAlexW4395085048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.