Evidence map›Paper›PMID 38660320›Full record

ArticleObstetric medicine2024

Aorta pathology and pregnancy-related risks in adult congenital cardiac disease: does the aorta dilate during pregnancy?

Anne-Sophie Ceuppens, Pieter De Meester, Alexander Van De Bruaene, Jens-Uwe Voigt, Kristel Van Calsteren, Werner Budts, Els Troost

Open access · greenAbstract read
In one paragraph

Article in Obstetric medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anne-Sophie CeuppensCongenital and Structural Cardiology, University Hospitals Leuven, Belgium.ORCID https://orcid.org/0000-0002-7257-1035
Pieter De MeesterCongenital and Structural Cardiology, University Hospitals Leuven, Belgium.
Alexander Van De BruaeneCongenital and Structural Cardiology, University Hospitals Leuven, Belgium.
Jens-Uwe VoigtDepartment of Cardiovascular Sciences, KU Leuven - University of Leuven, Belgium.
Kristel Van CalsterenDepartment of Obstetrics and Gynecology, University Hospitals Leuven, Belgium.
Werner BudtsCongenital and Structural Cardiology, University Hospitals Leuven, Belgium.
Els TroostCongenital and Structural Cardiology, University Hospitals Leuven, Belgium.
KU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Aortic dilatation and pregnancy are major concerns in women with aortopathy (AOP). This single-centre retrospective analysis focuses on the evolution of aortic diameters during and after pregnancy in women with Marfan syndrome (MS), Turner syndrome (TS) and bicuspid aortic valve (BAV) aortopathy. Methods and results: Thirty-eight women who had one or more single pregnancies were included. The ascending aorta was measured during pregnancy and postpartum. During pregnancy, a significant increase of diameters of the sinus aortae (median 1.4 mm; [-1.3; 3.8]) and ascending aorta (median 2.1 mm; [0.0; 4.0]) was noted. Systemic hypertension gives dilation of the aorta, but it did not influence the overall trajectory during pregnancy. Conclusion: Significant aortic dilatation is noted during pregnancy in women with underlying AOP, even persisting in the long term. Pre-existing systemic hypertension is associated with larger aortic diameters prior to pregnancy. More research on a larger study population however is needed.

Indexed as

Aortopathybicuspid aortic valvecardiovascularMarfan syndromepregnancy complicationsTurner syndrome

Identifiers

PMID38660320
PMCPMC11037198
OpenAlexW4322744524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.