ArticleJACC. Asia2024
Sex Differences in the Association Between Depression and Incident Cardiovascular Disease.
Article in JACC. Asia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Cost-effectiveness analysis of early antihypertensive treatment for hypertension detected at health screening.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Life's Simple 7, depressive symptoms, cognitive performance, and their associations with all-cause mortality among middle-aged urban adults.GeroScience · 2026Article
- The interplay between loneliness, cortisol, and NK cell function: The role of cortisol in NK cell dysfunction.Psychoneuroendocrinology · 2026Article
- Anxiety and Depression in Women's Cardiovascular Health: Risk Modifiers, Mechanisms and Clinical Implications.Journal of cardiovascular development and disease · 2026Review
- Genetic perspectives on the comorbidity of anxiety and mood disorders with cardiovascular disease.Nature cardiovascular research · 2026Review
- Determinants of Maximal Oxygen Consumption in Cardiac Rehabilitation Patients: The Role of Sex.Journal of clinical medicine · 2026Article
- Association between depression and risk of ischaemic stroke in patients with atrial fibrillation.European heart journal open · 2026Article
- Depressive symptoms and association with prevalent cardiovascular disease: A cross-sectional analysis in Port-au-Prince, Haiti.PLOS mental health · 2026Article
- Depression and Heart Failure in US Veterans.JAMA network open · 2025Article
- Trajectories of health conditions predict cardiovascular disease risk among middle-aged and older adults: a national cohort study.Frontiers in nutrition · 2025Article
- The impact of grandchild caregiving on depression among grandparents: a scoping review.Frontiers in public health · 2025Article
- Dietary inflammatory index mediation lifestyle patterns and depression among women with osteopenia or osteoporosis.Frontiers in nutrition · 2025Article
- The Functional Profile, Depressive Symptomatology, and Quality of Life of Older People in the Central Alentejo Region: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Sex Differences in the Association of Depression Symptoms and Cardiovascular Disease in Adults in the United States.American journal of health promotion : AJHP · 2024Article
- Anxiety and depression are associated with heightened risk of incident deep vein thrombosis: Mediation through stress-related neural mechanisms.American journal of hematology · 2024Article
- Article
- Recommendations for the Application of Sex and Gender Medicine in Preclinical, Epidemiological and Clinical Research.Journal of personalized medicine · 2024Review
- Depression and Incident Cardiovascular Disease.JACC. Asia · 2024Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Depression is a known risk factor for cardiovascular disease (CVD), but the potential sex differences in this association remain unclear. Objectives: The aim of this study was to investigate the association between depression and subsequent CVD events, and to explore potential sex differences. Methods: The authors conducted a retrospective analysis using the JMDC Claims Database between 2005 and 2022. The study population included 4,125,720 individuals aged 18 to 75 years without a history of cardiovascular disease or renal failure and missing data at baseline. Participants were followed up for a mean of 1,288 days to assess the association between depression and subsequent CVD events, such as myocardial infarction, angina pectoris, stroke, heart failure, and atrial fibrillation. Results: Our analysis revealed a significant association between depression and subsequent composite CVD events in both men and women, with a stronger association observed in women. The HR for the composite endpoint was 1.64 (95% CI: 1.59-1.70) in women and 1.39 (95% CI: 1.35-1.42) in men after multivariable adjustment ( Conclusions: Our study provides evidence of a significant association between depression and subsequent CVD events in both men and women, with a more pronounced association observed in women. These findings highlight the importance of addressing depression and tailoring prevention and management strategies according to sex-specific factors.
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