Evidence map›Paper›PMID 38660038›Full record

ArticleMethodsX2024

Modified turbidometric microassay for the measurement of sulfate in plasma and urine.

Prasidhee Vijayakumar, Avis McWhinney, Yvonne A Eiby, Paul A Dawson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Prasidhee VijayakumarMater Research Institute, The University of Queensland, Woolloongabba, QLD, Australia.
Avis McWhinneyPathology Department, Mater Health Services, South Brisbane, QLD, Australia.
Yvonne A EibyUQ Centre for Clinical Research and Perinatal Research Centre, The University of Queensland, Brisbane, Australia.
Paul A DawsonMater Research Institute, The University of Queensland, Woolloongabba, QLD, Australia.
The University of Queensland · AUMater Health Services · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulfate is the fourth most abundant anion in circulation. Despite being an essential nutrient for healthy growth and development, sulfate is not routinely measured in clinical settings. In research settings, animal studies have shown that hyposulfatemia and hypersulfaturia are associated with adverse developmental outcomes. Those findings have increased interest in measuring plasma and urine sulfate levels. In this study, we describe a modified assay to measure sulfate in low volumes of plasma and urine. •A streamlined microassay to measure sulfate levels using a microtiter plate format was developed.•To determine the robustness of the assay, this method assessed reagent stability and concentrations, as well as absorbance at different wavelengths and following a range of incubation times.•The optimized microassay was used to measure sulfate level in pig plasma and urine samples, which were compared to a validated ion chromatography method.

Indexed as

Barium chlorideSulfate assaySulfatemiaTurbidometric microassay for measurement of inorganic sulfate

Identifiers

PMID38660038
PMCPMC11041906
OpenAlexW4394936193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.