Evidence map›Paper›PMID 38659993›Full record

ArticleFrontiers in microbiology2024

Association between oral microbiome and five types of respiratory infections: a two-sample Mendelian randomization study in east Asian population.

Jiawei He, Ningfeng Mao, Wenliang Lyu, Shuhan Zhou, Yang Zhang, Zhiyi Liu, Zixuan Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Human Oral-AssociatedMicroorganisms · 2026
    Review
  4. Oral Microbiome and Constipation: A Causal Link Revealed by Mendelian Randomization.JGH open : an open access journal of gastroenterology and hepatology · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Microbiome and its role in bronchiectasis.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jiawei HeInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Ningfeng MaoInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Wenliang LyuInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Shuhan ZhouInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Yang ZhangInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Zhiyi LiuInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Zixuan XuInstitute of Epidemic Diseases, Hubei University of Chinese Medicine, Wuhan, Hubei, China.
Hubei University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the causal relationship between the oral microbiome and specific respiratory infections including tonsillitis, chronic sinusitis, bronchiectasis, bronchitis, and pneumonia, assessing the impact of genetic variations associated with the oral microbiome. Methods: Mendelian randomization was used to analyze genetic variations, leveraging data from genome-wide association studies in an East Asian cohort to identify connections between specific oral microbiota and respiratory infections. Results: Our analysis revealed that Discussion: These findings underscore the significant impact of the oral microbiome on respiratory health, suggesting potential strategies for disease prevention and management through microbiome targeting. The study highlights the complexity of microbial influences on respiratory infections and the importance of further research to elucidate these relationships.

Indexed as

causal effectMendelian randomizationsoral microbiomerespiratory infectionrespiratory tract diseases

Identifiers

PMID38659993
PMCPMC11039966
OpenAlexW4394689218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.