Evidence map›Paper›PMID 38659981›Full record

ArticleFrontiers in microbiology2024

Towards facilitated interpretation of shotgun metagenomics long-read sequencing data analyzed with KMA for the detection of bacterial pathogens and their antimicrobial resistance genes.

Mathieu Gand, Indre Navickaite, Lee-Julia Bartsch, Josephine Grützke, Søren Overballe-Petersen, Astrid Rasmussen, Saria Otani, Valeria Michelacci, Bosco Rodríguez Matamoros, Bruno González-Zorn and 7 more

Abstract read
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Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Detection ofFood chemistry. Molecular sciences · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Mathieu GandTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Indre NavickaiteDepartment of Bacteriology, Animal and Plant Health Agency, Weybridge, United Kingdom.
Lee-Julia BartschDepartment of Biological Safety, German Federal Institute for Risk Assessment, Berlin, Germany.
Josephine GrützkeDepartment of Biological Safety, German Federal Institute for Risk Assessment, Berlin, Germany.
Søren Overballe-PetersenBacterial Reference Center, Statens Serum Institute, Copenhagen, Denmark.
Astrid RasmussenBacterial Reference Center, Statens Serum Institute, Copenhagen, Denmark.
Saria OtaniNational Food Institute, Technical University of Denmark, Kongens Lyngby, Denmark.
Valeria MichelacciDepartment of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy.
Bosco Rodríguez MatamorosDepartment of Animal Health, Complutense University of Madrid, Madrid, Spain.
Bruno González-ZornDepartment of Animal Health, Complutense University of Madrid, Madrid, Spain.
Michael S M BrouwerWageningen Bioveterinary Research Part of Wageningen University and Research, Lelystad, Netherlands.
Lisa Di MarcantonioIstituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", Teramo, Italy.
Bram BloemenTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Kevin VannesteTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Nancy H C J RoosensTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Manal AbuOunDepartment of Bacteriology, Animal and Plant Health Agency, Weybridge, United Kingdom.
Sigrid C J De KeersmaeckerTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metagenomic sequencing is a promising method that has the potential to revolutionize the world of pathogen detection and antimicrobial resistance (AMR) surveillance in food-producing environments. However, the analysis of the huge amount of data obtained requires performant bioinformatics tools and databases, with intuitive and straightforward interpretation. In this study, based on long-read metagenomics data of chicken fecal samples with a spike-in mock community, we proposed confidence levels for taxonomic identification and AMR gene detection, with interpretation guidelines, to help with the analysis of the output data generated by KMA, a popular

Indexed as

antimicrobial resistancebioinformaticsdatabaseKMAmetagenomicsONTpathogensresults interpretation

Identifiers

PMID38659981
PMCPMC11042533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.