Evidence map›Paper›PMID 38659962›Full record

ArticleResearch square2024

Inferring Bladder Cancer Evolution from Mucosal field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping.

Bogdan Czerniak, Sangkyou Lee, Sung Yun Jung, Pawel Kus, Jolanta Bondaruk, June Lee, Roman Jaksik, Nagireddy Putluri, Khanh Dinh, David Cogdell and 11 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 2 countries.

Bogdan CzerniakThe University of Texas MD Anderson Cancer Center.ORCID 0000-0002-8289-9173
Sangkyou LeeThe University of Texas MD Anderson Cancer Center.
Sung Yun JungBaylor College of Medicine.ORCID 0000-0003-1521-7977
Pawel KusSilesian Univerity of Technology.ORCID 0000-0002-4367-9821
Jolanta BondarukThe University of Texas MD Anderson Cancer Center.
June LeeThe University of Texas MD Anderson Cancer Center.
Roman JaksikSilesian University of Technology.
Nagireddy PutluriBaylor College of Medicine.
Khanh DinhIrving Institute for Cancer Dynamics, Columbia University.
David CogdellThe University of Texas MD Anderson Cancer Center.
Huiqin ChenThe University of Texas MD Anderson Cancer Center.
Yishan WangThe University of Texas MD Anderson Cancer Center.
Jiansong ChenThe University of Texas MD Anderson Cancer Center.
Neema NevaiThe University of Texas MD Anderson Cancer Center.
Colin DinneyThe University of Texas MD Anderson Cancer Center.
Cathy MendelsohnColumbia University.
David McConkeyJohns Hopkins Greenberg Bladder Cancer Institute, Johns Hopkins University.
Richard BehringerUniversity of Texas M. D. Anderson Cancer Center.
Charles GuoThe University of Texas MD Anderson Cancer Center.
Peng WeiThe University of Texas MD Anderson Cancer Center.
Marek KimmelRice University.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USSilesian University of Technology · PLColumbia University · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
NCI NIH HHS P30 CA125123
6 · The paper itself

Abstract

Multi-platform mutational, proteomic, and metabolomic spatial mapping was used on the whole-organ scale to identify the molecular evolution of bladder cancer from mucosal field effects. We identified complex proteomic and metabolomic dysregulations in microscopically normal areas of bladder mucosa adjacent to dysplasia and carcinoma

Identifiers

PMID38659962
PMCPMC11042420
OpenAlexW4394681247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.